Clinical Trials in Birmingham, Alabama

Find clinical trials in Birmingham, Alabama. Discover local research opportunities and treatment options in your area.

1113 Active Trials Found in Birmingham

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Minds and Mentors Program- R33

NCT ID: NCT05363371

The Minds and Mentors Program- R33 is a research study that aims to find out how effective a new group treatment program is for individuals dealing with opioid use disorder. In this trial, particip...

Recruiting

Phase: NA Conditions: Substance Use Disorders, Opioid Use Disorder +1 more

Multisite Implementation of COMPRENDO

NCT ID: NCT06055296

The COMPRENDO study is exploring a new way to help families of Hispanic children with cancer navigate the clinical trial process. This clinical trial will compare a supportive program called peer n...

Recruiting

Phase: NA Conditions: Pediatric Cancer

Implementation of Whole Genome Sequencing as Screening in a Diverse Cohort of Healthy Infants

NCT ID: NCT05161169

This clinical trial is studying the use of whole genome sequencing, a type of genetic testing, to check for health risks in healthy newborns. Researchers want to see if this technology can help ide...

Recruiting

Phase: NA Conditions: Genetic Predisposition to Disease, Hereditary Diseases

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

NCT ID: NCT05543616

This clinical trial is looking at a new COVID-19 vaccine designed for healthy children. The goal is to understand how safe the vaccine is, what side effects might occur, and how well it helps the i...

Recruiting

Phase: PHASE2 Conditions: COVID-19, Severe Acute Respiratory Syndrome Coronavirus 2 +1 more

Ribociclib (LEE011) Rollover Study for Continued Access

NCT ID: NCT02934568

This clinical trial is called the Ribociclib Rollover Study, and it aims to give patients continued access to a treatment called ribociclib (LEE011). This study is for people who are already partic...

Recruiting

Phase: PHASE2 Conditions: Continued Access to Study Treatment(s), Cancers With a Mass, Bulky Tumor, Nodule, Lump, Advanced Cancer, Advanced Solid Tumors, Advanced Solid Malignancies

Phase 2 Trial of HY209gel in Atopic Dermatitis Patients

NCT ID: NCT06024499

This clinical trial is studying a new treatment called HY209gel for people with atopic dermatitis, which is a skin condition that causes itchy, inflamed skin. The trial is currently looking for par...

Recruiting

Phase: PHASE2 Conditions: Atopic Dermatitis, Atopic Dermatitis Eczema +1 more

Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

NCT ID: NCT01656603

This clinical trial is studying the safety of a new type of cord blood treatment for patients with certain blood disorders. Cord blood, which comes from the umbilical cord after a baby is born, con...

Recruiting

Phase: PHASE2 Conditions: Infusion Reactions

A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD)

NCT ID: NCT04042844

This clinical trial is studying the effects of a single dose of a treatment called BRTX 100 on patients suffering from chronic lumbar disc disease (cLDD), which is a condition that causes ongoing b...

Recruiting

Phase: PHASE2 Conditions: Lumbar Disc Disease

A Study to Evaluate Upadacitinib in Combination With Topical Corticosteroids in Adolescent and Adult Participants With Moderate to Severe Atopic Dermatitis

NCT ID: NCT03568318

This study tested how well the oral medicine upadacitinib works when added to topical corticosteroids for adults and teens with moderate-to-severe atopic dermatitis (eczema). It included people age...

Enrolling by invitation

Phase: PHASE3 Conditions: Atopic Dermatitis

ViTAA Registry Pre- and Post-Operative Monitoring for Endovascular Aortic Aneurysm Repair and Serial Monitoring for AAA

NCT ID: NCT05004051

The ViTAA Registry study is looking at patients with abdominal aortic aneurysms, which are bulges in the aorta that can be serious if not treated. This study aims to collect important information a...

Recruiting

Conditions: Abdominal Aortic Aneurysms

PREDICT Trial: PRospective Evaluation of NTM Disease In CysTic Fibrosis

NCT ID: NCT02073409

This is an observational study called PREDICT (with a follow-on PART B called PATIENCE) focused on people with cystic fibrosis (CF) who have a positive test for non-tuberculous mycobacteria (NTM) i...

Enrolling by invitation

Conditions: Cystic Fibrosis

PATIENCE Trial: Prospective Algorithm for Treatment of NTM in Cystic Fibrosis

NCT ID: NCT02419989

This is an observational study called PATIENCE, which follows people with cystic fibrosis (CF) who have a lung infection caused by non-tuberculous mycobacteria (NTM). It does not test a new drug; i...

Enrolling by invitation

Conditions: Cystic Fibrosis

Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

NCT ID: NCT04660760

This clinical trial is studying a new treatment approach for adults with advanced stomach or gastroesophageal junction cancer that has come back or spread after previous treatments. The trial speci...

Recruiting

Phase: PHASE2 Conditions: Metastatic Gastroesophageal Junction Adenocarcinoma, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 +29 more

I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients

NCT ID: NCT04488081

The I-SPY COVID-19 Trial is a research study designed to find new treatments for critically ill patients who have COVID-19. This trial aims to quickly test different promising medications to see if...

Recruiting

Phase: PHASE2 Conditions: COVID-19

LOWER: Lomitapide Observational Worldwide Evaluation Registry

NCT ID: NCT02135705

The LOWER study is looking at the long-term safety and effectiveness of a medication called lomitapide for patients with a rare genetic condition known as Homozygous Familial Hypercholesterolemia, ...

Recruiting

Conditions: Homozygous Familial Hypercholesterolemia

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

NCT ID: NCT01574053

The Enroll-HD study is a large, ongoing research project focused on Huntington's Disease (HD), a genetic condition that affects movement, thinking, and behavior. This study combines data from previ...

Recruiting

Conditions: Huntington's Disease

Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies

NCT ID: NCT04137900

This clinical trial is investigating a new treatment called TAB004, which is a type of medicine known as a monoclonal antibody. The trial aims to see how safe TAB004 is, especially when given alone...

Recruiting

Phase: PHASE1 Conditions: Metastatic Solid Tumor, Advanced Unresectable Solid Tumor

A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )

NCT ID: NCT04849728

This clinical trial, called NATiV3, is studying a new treatment called lanifibranor for adults with a liver condition known as Nonalcoholic Steatohepatitis (NASH) and fibrosis stages F2 or F3. NASH...

Recruiting

Phase: PHASE3 Conditions: NASH - Nonalcoholic Steatohepatitis

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

NCT ID: NCT05338697

The VERIFY trial is studying how certain biological markers can help predict how well someone will recover from a stroke, particularly focusing on their ability to move their arms and hands. This r...

Recruiting

Conditions: Stroke, Stroke, Acute +2 more

Study of Eblasakimab in Male or Female Moderate-to-Severe Atopic Dermatitis Patients Previously Treated With Dupilumab

NCT ID: NCT05694884

This clinical trial is studying a new treatment called eblasakimab for people with moderate-to-severe atopic dermatitis, a skin condition that causes itching and inflammation. Participants in this ...

Recruiting

Phase: PHASE2 Conditions: Atopic Dermatitis