LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

NCT ID: NCT04752722

The LEGEND Study is a clinical trial that is investigating a new treatment called EG-70 for patients with a type of bladder cancer known as non-muscle invasive bladder cancer (NMIBC). Specifically,...

Recruiting

Phase: PHASE1 Conditions: Superficial Bladder Cancer, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

NCT ID: NCT05457283

This clinical trial is studying the safety and effectiveness of a medication called finerenone when taken alongside other common treatments (ACE inhibitors or ARBs) for children and young adults ag...

Recruiting

Phase: PHASE3 Conditions: Chronic Kidney Disease, Children +1 more

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

NCT ID: NCT06615479

This clinical trial, called QUINTESSENTIAL-2, is testing a new treatment called BMS-986393 to see how well it works compared to standard treatments for adults with relapsed or refractory multiple m...

Recruiting

Phase: PHASE3 Conditions: Relapsed or Refractory Multiple Myeloma (RRMM)

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

NCT ID: NCT06979453

This clinical trial is studying a medication called Deucravacitinib (also known as BMS-986165) to see how well it works, its safety, and how the body processes the drug in adolescents aged 12 to 17...

Recruiting

Phase: PHASE3 Conditions: Plaque Psoriasis

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

NCT ID: NCT07064473

This clinical trial is studying whether a new medicine called vicadrostat, when taken together with an existing diabetes medicine called empagliflozin, can help lower the risk of heart problems in ...

Recruiting

Phase: PHASE3 Conditions: Hypertension, Diabetes Mellitus, Type 2 +1 more

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

NCT ID: NCT03486873

This clinical trial, called MK-3475-587, is looking into the long-term safety and effectiveness of a treatment called pembrolizumab (also known as MK-3475) for patients with advanced tumors. If you...

Recruiting

Phase: PHASE3 Conditions: Solid Tumors, Hematologic Malignancies

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

NCT ID: NCT03813407

This clinical trial is studying a medication called sodium zirconium cyclosilicate (SZC) to see how safe and effective it is for treating high potassium levels (hyperkalaemia) in children under 18 ...

Recruiting

Phase: PHASE3 Conditions: Hyperkalaemia

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

NCT ID: NCT05006716

This clinical trial is studying a new treatment called BGB-16673 for patients with specific types of B-cell cancers, such as Marginal Zone Lymphoma, Follicular Lymphoma, and Chronic Lymphocytic Leu...

Recruiting

Phase: PHASE1 Conditions: Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma +7 more

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

NCT ID: NCT05564390

The MYELOMATCH trial is a research study designed to help people with certain types of blood cancers, specifically acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). The main goal of ...

Recruiting

Phase: PHASE2 Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

NCT ID: NCT05675410

This clinical trial is studying whether adding two specific drugs, brentuximab vedotin and nivolumab, to the standard treatment for early-stage Hodgkin lymphoma can help patients live longer and ex...

Recruiting

Phase: PHASE3 Conditions: Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

NCT ID: NCT06044337

This long-term extension study is testing litifilimab (BIIB059) for adults with active cutaneous lupus erythematosus (CLE)—including subacute CLE and chronic CLE—with or without mild systemic lupus...

Enrolling by invitation

Phase: PHASE3 Conditions: Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

NCT ID: NCT06172296

This clinical trial is studying a new treatment approach for children with high-risk neuroblastoma, a type of cancer that affects nerve cells. The researchers want to find out if combining a medici...

Recruiting

Phase: PHASE3 Conditions: Neuroblastoma, Ganglioneuroblastoma, Nodular

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

NCT ID: NCT06461897

This clinical trial is studying two treatments for children aged 2 to less than 12 years who have moderate to severe atopic dermatitis (AD), a skin condition that causes rashes and itching. The tri...

Recruiting

Phase: PHASE3 Conditions: Atopic Dermatitis

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

NCT ID: NCT06883305

This clinical trial is investigating the effectiveness and safety of a medication called Tezepelumab for adults with moderate to very severe Chronic Obstructive Pulmonary Disease (COPD). COPD is a ...

Recruiting

Phase: PHASE3 Conditions: Chronic Obstructive Pulmonary Disease (COPD)

A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque Psoriasis

NCT ID: NCT06973291

This clinical trial is designed to compare two medications, zasocitinib (also known as TAK-279) and deucravacitinib, to see which one is more effective in treating adults with moderate-to-severe pl...

Recruiting

Phase: PHASE3 Conditions: Plaque Psoriasis

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

NCT ID: NCT06989112

The DESTINY-Endometrial01 trial is a research study looking at new treatment options for women with a specific type of advanced or recurrent endometrial cancer, which is a cancer of the uterus. Thi...

Recruiting

Phase: PHASE3 Conditions: Endometrial Cancer

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

NCT ID: NCT07054515

This clinical trial is testing a new oral medicine called nizubaglustat (AZ-3102) to see if it is safe and helpful for people with certain rare genetic diseases that affect the brain and nervous sy...

Recruiting

Phase: PHASE3 Conditions: GM1 Gangliosidosis, GM2 Gangliosidosis +1 more

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis

NCT ID: NCT07082543

This clinical trial is testing an oral medicine called nizubaglustat (AZ-3102) to see if it is safe and helpful for children and young people who have certain rare genetic conditions called GM1 or ...

Recruiting

Phase: PHASE3 Conditions: Gangliosidoses, GM2, Gangliosidosis, GM1

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)

NCT ID: NCT07082725

This clinical trial is studying a new oral medicine called nizubaglustat (AZ-3102) to see if it is safe and helpful for people with Niemann-Pick Type C disease, a rare condition that affects the br...

Recruiting

Phase: PHASE3 Conditions: Niemann-Pick Type C Disease

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Clinical Trials in Calgary, Alberta

563 Active Trials Found in Calgary

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque Psoriasis

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of GM1 Gangliosidosis or GM2 Gangliosidosis

A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)