Systemic Lupus Erythematosus in Gullah Health

Launched by MEDICAL UNIVERSITY OF SOUTH CAROLINA · Sep 18, 2008

Keywords

ClinConnect Summary

**Summary of the Clinical Trial: Systemic Lupus Erythematosus in Gullah Health**

This clinical trial is studying systemic lupus erythematosus (SLE), an autoimmune disease where the body mistakenly attacks its own tissues, affecting various organs and causing a range of symptoms. The focus is on the Gullah community of African Americans from the Sea Islands of South Carolina and Georgia, who are at a higher risk for SLE. Researchers believe that certain genetic factors, along with environmental influences, may play a role in the development of this disease. The Gullah population is unique because they share a similar genetic background, which helps scientists better understand how these factors contribute to SLE.

To participate in this study, you need to be at least 2 years old, identify as Gullah from the Sea Islands, and either have a diagnosis of SLE (with at least 4 out of 11 specific symptoms) or be a relative of someone with SLE. Healthy individuals from the Gullah community can also take part as control subjects. Participants will be asked to provide informed consent and will be involved in activities that help researchers gather important information about SLE. This study aims to improve understanding of the disease and ultimately lead to better treatments for those affected. If you’re interested or know someone who might be eligible, this could be a valuable opportunity to contribute to important research.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 2 years and above;
• • Self-identified as African-American "Gullah" from the Sea Island region of South Carolina;
• • Have had at least 4 of the 11 diagnostic criteria for SLE as designated by the American College of Rheumatology (ACR), be a relative of a known SLE patient, or be an unrelated healthy Gullah control;
• • Ability to speak and understand English;
• • Ability and willingness to give informed consent
• Exclusion Criteria:
• • Race defined by participant as other than Black or African-American;
• • Being a prisoner, mentally ill patient, or institutionalized individual;
• • Unwilling or unable to give informed consent