A Comparison of Exparel to Bupivacaine in TAP Block for Abdominal Gynecologic Surgery
Launched by ABINGTON MEMORIAL HOSPITAL · Oct 3, 2017
Trial Information
Current as of May 14, 2025
Unknown status
Keywords
ClinConnect Summary
The proposed pilot study is evaluating the use of Exparel ™ in an anesthesia protocol for patients undergoing major lower abdominal gynecologic surgery. Exparel ™ is a formulation of liposomal bupivicaine that is reputed to have a much longer duration of action compares to bupivacaine. Exparel™ has been originally demonstrated to be safe and effective in bunionectomy and hemorrhoidectomy. It has recently gained FDA approval for all surgical site infiltration including TAP (Transversus Abdominis Planus block) blocks. Exparel™ has also been studied in other procedures and demonstrated reducti...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • all patients undergoing planned exploratory laparotomy
- • TAP blocks placed after the laparotomy incision is closed, but before the patient is awake, and placed under ultrasound guidance with correct identification of the correct abdominal plane.
- • Consent for TAP block signed by patients preoperatively by anesthesiology
- Exclusion Criteria:
- • All pregnant patients
- • All patients under 18 years of age
- • minimally invasive surgery such as laparoscopy or robotic assisted laparoscopy
- • medical contraindications to use of bupivacaine or liposomal bupivacaine such as severe hepatic and/or renal disease
About Abington Memorial Hospital
Abington Memorial Hospital is a leading healthcare institution dedicated to providing high-quality patient care and advancing medical research. As a prominent clinical trial sponsor, the hospital is committed to investigating innovative treatment options and therapies to improve patient outcomes. With a focus on collaboration and ethical research practices, Abington Memorial Hospital engages in a variety of clinical studies across multiple specialties, fostering an environment where clinical excellence and scientific inquiry intersect to enhance healthcare delivery.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Abington, Pennsylvania, United States
Patients applied
Trial Officials
Heidi Ching, MD
Principal Investigator
OB GYN Resident
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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