Immune Mediators and Metabolites to Stratify Systemic Lupus Erythematosus Patients at High Risk of Cardio Vascular Diseases

Launched by UNIVERSITY HOSPITAL, BORDEAUX · Feb 17, 2020

Keywords

ClinConnect Summary

This clinical trial is studying how specific immune-related substances in the blood (called immunometabolites) can help identify patients with Systemic Lupus Erythematosus (SLE) who are at a higher risk of developing heart and blood vessel diseases. SLE is an autoimmune disease, and research shows that patients, especially young women, are more likely to experience heart problems compared to healthy individuals. The goal of this study is to understand how these substances could serve as new markers to predict cardiovascular risk in SLE patients, which could lead to better management of their health.

To participate in this trial, you need to be an adult over 18 years old with a confirmed diagnosis of SLE. You should also be able to give informed consent, meaning you understand the study and agree to participate. If you are pregnant, breastfeeding, or legally unable to consent, you would not be eligible. Participants will have the opportunity to undergo tests that assess their heart health and immune system, helping researchers learn more about the connection between SLE and cardiovascular diseases. This could ultimately help in providing better care and prevention strategies for those living with SLE.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult patient aged over 18 years old.
• • SLE diagnosis according to the 2019 European League Against Rheumatism (EULAR) / American College of Rheumatology (ACR) Classification Criteria for Systemic Lupus Erythematosus
• • Having signed an informed consent (at the latest on the day of inclusion and before any examination required by research).
• Exclusion Criteria:
• • Pregnancy or breast-feeding for woman.
• • Person concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent