O2 Versus CPAP Treatment of Patients Undergoing SIPE Therapy (OCTOPUS)

Launched by DALARNA COUNTY COUNCIL, SWEDEN · Mar 11, 2020

Keywords

ClinConnect Summary

The OCTOPUS trial is studying how to best treat a condition called swimming-induced pulmonary edema (SIPE), which can cause serious breathing difficulties when someone is swimming. The researchers want to compare two types of treatments: oxygen alone and a method called continuous positive airway pressure (CPAP). The goal is to find out which treatment works better for people experiencing SIPE before they reach the hospital.

To participate in this trial, you need to be at least 18 years old and have been diagnosed with SIPE, meaning your oxygen levels are low (91% or less). If you have certain heart or breathing conditions, or if you are unable to give consent, you may not qualify. If you join the study, you will receive either oxygen or CPAP to see how well it helps your breathing. The trial is currently looking for participants, and it aims to improve our understanding of how to treat this condition effectively.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • clinical diagnosis of swimming induced pulmonary edema (SIPE) with need of acute treatment (oxygen saturation ≤91%)
• • 18 years and older
• • informed consent
• Exclusion Criteria:
• • declined consent
• • suspected acute coronary syndrome
• • severe asthma diagnosed together with pulmonary edema where beta-agonist-inhalation is needed prior to treatment of pulmonary edema
• • hemodynamic instability or decreased consciousness