Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules

Launched by CITY OF HOPE MEDICAL CENTER · Feb 4, 2022

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to diagnose thyroid nodules, which are lumps in the thyroid gland that can sometimes be cancerous. Researchers want to develop a test that uses DNA from small samples taken with a needle biopsy to tell if a nodule is cancer (malignant) or not (benign). This could help avoid unnecessary surgeries for patients when the nodules are actually harmless.

To participate in the trial, you need to be over 18 years old and have a thyroid nodule that requires a needle biopsy. It's important that you are able to make decisions about your health and can provide consent for your tissue and medical information to be used in the study. The goal is to improve how doctors diagnose thyroid nodules, making it easier for patients to understand their condition and reducing the stress of potential surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients without impaired decision-making capacity and who are undergoing needle biopsies for thyroid nodule diagnosis
• • Over the age of 18
• • Any gender, race and ethnicity
• • Patients must provide informed consent prior to use of their tissues and clinical data
• Exclusion Criteria:
• • Children are excluded from the study, since the biology of children thyroid nodules is different from adults