Electroclinical Features of Sudden Unexpected Death in Epilepsy (SUDEP) : a Multi-center Observational Study

Launched by LIU YONGHONG · Jun 14, 2022

Keywords

ClinConnect Summary

This study is an observational project that looks at people with epilepsy who have had Sudden Unexpected Death in Epilepsy (SUDEP) or a near-SUDEP event. The goal is to understand what happens before and during these events and to explore brain activity patterns captured on video EEG (brain waves recorded with video). Researchers hope to identify markers that could help prevent SUDEP in the future. It’s a multicenter study in China, led by Xijing Hospital in Xi’an, and plans to enroll about 30 participants who have already experienced SUDEP or near-SUDEP.

Who can take part? The study includes all sexes and ages (children, adults, and older adults) and will enroll people with epilepsy who have SUDEP or near-SUDEP, with consent from a relative or caregiver. To participate, doctors must confirm the SUDEP/near-SUDEP diagnosis and obtain written permission from a family member or caregiver. Participants will undergo a 24-hour video-EEG monitoring test using standard equipment to collect data, along with routine tests like eyes-open/closed checks, intermittent photic stimulation, and hyperventilation. The study is observational (not testing a drug or device) and aims to track SUDEP events and related EEG findings from 2022 to 2024.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with epilepsy who meet SUDEP or near-SUDEP diagnosis,
• • Giving written informed consent to participate in the study from relatives or caregivers.
• Exclusion Criteria:
• • Refusing to recruitment from relatives or caregivers.