Evaluation of HRCT Patterns in Systemic Sclerosis-associated Interstitial Lung Disease

Launched by CENTRAL HOSPITAL, NANCY, FRANCE · Jul 29, 2022

Keywords

ClinConnect Summary

This clinical trial is researching how different patterns seen in high-resolution chest CT scans (HRCT) can help understand lung problems in patients with systemic sclerosis (SSc), an autoimmune disease that can affect many parts of the body. About 50% of people with systemic sclerosis develop interstitial lung disease (ILD), which can be serious and is a leading cause of death for these patients. The study aims to classify these lung issues based on specific changes seen in the scans, which could help doctors better predict how the disease will progress in each patient.

To participate in this trial, patients need to have a confirmed diagnosis of systemic sclerosis and show signs of interstitial lung disease on their chest scans. The study is open to adults aged 65 to 74, regardless of gender. Participants can expect to have their HRCT scans analyzed as part of the research, helping to improve understanding and treatment of lung disease related to systemic sclerosis. It's important to note that individuals with other lung conditions that could mimic SSc-related ILD, like lung cancer or silicosis, will not be eligible for the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with systemic sclerosis according to 2013 ACR/EULAR criteria
• • Patients with interstitial lung disease on HRCT chest
• Exclusion Criteria:
• • Patients with an alternative diagnosis of SSc-associated ILD (silicosis, sarcoidosis, lung cancer or other significant lung abnormalities)