Sonazoid in Myocardial Perfusion Imaging

Launched by LONDON NORTH WEST HEALTHCARE NHS TRUST · Nov 24, 2022

Keywords

ClinConnect Summary

Ultrasound contrast agents are gas-filled microbubbles that enhance the visualisation of cardiac structures, function and blood flow. Myocardial contrast echocardiography enables us to visualise myocardial perfusion and provides incremental information for diagnosis of coronary artery disease (CAD) and prognosis beyond wall motion assessment .

Using ultrasound at low acoustic power (low/intermediate MI) causes the microbubbles to oscillate resulting in giving off non-linear signals which are different from tissues which gives off linear signals.

The first contrast agents were used in 1968...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Positive and normal Clinical SE
• • Able to provide informed consent
• Exclusion Criteria:
• • Unable / unwilling to give informed consent
• • Allergy to Perfluorobutane
• • Egg allergy
• • Patients with right to left arteriovenous cardiac or pulmonary shunt
• • Unstable heart disease
• • Serious pulmonary disease
• • Pregnancy or lactation Women of child bearing potential (defined as not chemically or surgically sterilised or post menopausal)