Trials
Search / Trial NCT05650957

PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia

Launched by ACADEMISCH MEDISCH CENTRUM - UNIVERSITEIT VAN AMSTERDAM (AMC-UVA) · Dec 13, 2022

Trial Information

Current as of January 22, 2025

Completed

Keywords

Mechanical Ventilation Acute Respiratory Distress Syndrome Ventilation Practice Pulmonary Infection Covid 19

ClinConnect Summary

Early on in the pandemic, it was frequently proposed that ARDS caused by COVID-19 and ARDS caused by another cause were distinct in a number of ways. COVID-19 related ARDS phenotypes have been suggested, based on differences in respiratory system compliance (Crs) and the severity of the hypoxemia. Other reports have even suggested that lung-protective ventilation strategies for patients with ARDS caused by COVID-19 should differ from those used before the pandemic.

The use of low tidal volumes (VT) and prone positioning, which have been shown to be useful in reducing death in patients with...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Cause for ARDS is COVID -19 (confirmed with polymerase chain reaction (PCR) and/or presence of typical abnormalities on chest computer tomography (CT) and/or X-ray) or a pulmonary infection from another origen
  • 2. Meeting a Berlin criteria for ARDS
  • 3. Invasive ventilation
  • Exclusion Criteria:
  • 1. Age \< 18 years
  • 2. Any form of non-invasive ventilation

Trial Officials

David MP van Meenen, PhD

Study Chair

Amsterdam UMC, location AMC

About Academisch Medisch Centrum Universiteit Van Amsterdam (Amc Uva)

The Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) is a leading academic medical center in the Netherlands, dedicated to advancing healthcare through innovative research, education, and patient care. Affiliated with the University of Amsterdam, AMC-UvA integrates clinical practice with cutting-edge biomedical research, fostering a multidisciplinary approach to medical challenges. The institution actively engages in clinical trials to enhance treatment options and improve patient outcomes, while promoting collaboration among healthcare professionals, researchers, and academic institutions globally. With a commitment to excellence and a focus on translational medicine, AMC-UvA plays a pivotal role in shaping the future of healthcare.

Locations

Amsterdam, , Netherlands

La Plata, , Argentina

São Paulo, , Brazil

São Paulo, , Brazil

Galway, , Ireland

Madrid, , Spain

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

Similar Trials