Effect of Aminophylline Bolus Versus Infusion on Recovery Time in Patients Undergoing Lumbar Spine Surgery

Launched by CAIRO UNIVERSITY · Dec 15, 2022

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called aminophylline on recovery time for patients undergoing lumbar spine surgery, which is a type of surgery on the lower back. Researchers want to find out if giving aminophylline before stopping the anesthesia helps patients wake up faster and be ready to breathe on their own sooner compared to giving it after the surgery is done.

To be eligible for this trial, participants should be healthy adults between the ages of 20 and 50 who are scheduled for specific types of back surgery. However, people with certain health issues, such as heart problems, kidney or liver disease, thyroid disorders, epilepsy, or those who are allergic to aminophylline, cannot participate. If you join the study, you can expect to receive either a bolus (a quick dose) or an infusion (a slower, continuous dose) of aminophylline, and researchers will monitor how quickly you recover from the anesthesia after your surgery. It's an important step to see if this approach can improve recovery for patients like you.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ASA I-II. 20-50 years old patients. Both sexes Patients undergoing single or double level lumbar laminectomy ,discectomy and/or fixation
• Exclusion Criteria:
• • Contraindications to the use of aminophylline as cardiac patients, patients with renal impairment, hepatic dysfunction, hypo or hyperthyroidism and epilepsy.
• • Patients who have hypersensitivity to aminophylline Emergency operations. Operative time exceeding 5 hours