Effect of Aminophylline Bolus Versus Infusion on Recovery Time in Patients Undergoing Lumbar Spine Surgery
Launched by CAIRO UNIVERSITY · Dec 15, 2022
Trial Information
Current as of January 14, 2025
Unknown status
Keywords
ClinConnect Summary
This clinical trial is studying the effects of a medication called aminophylline on recovery time for patients undergoing lumbar spine surgery, which is a type of surgery on the lower back. Researchers want to find out if giving aminophylline before stopping the anesthesia helps patients wake up faster and be ready to breathe on their own sooner compared to giving it after the surgery is done.
To be eligible for this trial, participants should be healthy adults between the ages of 20 and 50 who are scheduled for specific types of back surgery. However, people with certain health issues, such as heart problems, kidney or liver disease, thyroid disorders, epilepsy, or those who are allergic to aminophylline, cannot participate. If you join the study, you can expect to receive either a bolus (a quick dose) or an infusion (a slower, continuous dose) of aminophylline, and researchers will monitor how quickly you recover from the anesthesia after your surgery. It's an important step to see if this approach can improve recovery for patients like you.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • ASA I-II. 20-50 years old patients. Both sexes Patients undergoing single or double level lumbar laminectomy ,discectomy and/or fixation
- Exclusion Criteria:
- • Contraindications to the use of aminophylline as cardiac patients, patients with renal impairment, hepatic dysfunction, hypo or hyperthyroidism and epilepsy.
- • Patients who have hypersensitivity to aminophylline Emergency operations. Operative time exceeding 5 hours
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0
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