Continuous Adductor Canal Block in Fast Track Total Knee Arthroplasty
Launched by SAMUEL LUNENFELD RESEARCH INSTITUTE, MOUNT SINAI HOSPITAL · Jul 26, 2023
Trial Information
Current as of November 12, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a pain management technique called Continuous Adductor Canal Block (CACB) for patients undergoing total knee replacement surgery, which is often done on the same day without an overnight hospital stay. The goal is to see if using this method can provide longer-lasting pain relief, reduce the need for opioid painkillers, and improve the overall recovery experience for patients. Researchers believe that this technique may lead to better pain control with fewer side effects compared to traditional single shot pain relief methods.
To be eligible for the trial, participants must be at least 21 years old and scheduled for a primary knee replacement surgery. They should be in good health, not dependent on alcohol or drugs, and able to understand and cooperate with the treatment plan. Participants will experience a continuous delivery of local anesthetic through a small tube placed near the nerves in the leg, which is expected to help manage pain after surgery. The study will monitor various outcomes, including pain levels, recovery quality, and any side effects from the treatment. This research is important because it may lead to improved recovery methods for a common procedure, ultimately enhancing patients' quality of life.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients undergoing unilateral primary TKA in the fast track setting.
- • Patients older than 21 years of age, with American Society of Anesthesiologists (ASA)
- • Physical status I-III
- • No alcohol or drug dependency
- • Sufficient understand and co-operation about the perineural catheter.
- Exclusion Criteria:
- • Perioperative complication or discharge delay leading to hospital admission.
- • Chronic opioid use of morphine 30mg equivalent per day for last 2 consecutive weeks.
- • Allergy to the study medications;
- • Coagulopathy and platelet count \< 105/μL;
- • Patients with contraindications to the insertion of an epidural or adductor canal catheter (severe anatomic abnormalities or history of previous surgery at the site of catheter placement).
About Samuel Lunenfeld Research Institute, Mount Sinai Hospital
The Samuel Lunenfeld Research Institute at Mount Sinai Hospital is a leading biomedical research facility dedicated to advancing our understanding of human health and disease. Renowned for its innovative research programs, the institute focuses on areas such as cancer, genetics, and reproductive health, fostering collaboration among top-tier scientists and clinicians. With a commitment to translating research findings into clinical applications, the Samuel Lunenfeld Research Institute plays a pivotal role in the development of novel therapies and interventions, thereby contributing to improved patient outcomes and the advancement of medical science.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Toronto, Ontario, Canada
Patients applied
Trial Officials
Naveed Siddiqui, MD
Principal Investigator
Associate Professor
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported