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Search / Trial NCT05962970

Continuous Adductor Canal Block in Fast Track Total Knee Arthroplasty

Launched by SAMUEL LUNENFELD RESEARCH INSTITUTE, MOUNT SINAI HOSPITAL · Jul 26, 2023

Trial Information

Current as of November 12, 2025

Recruiting

Keywords

Orthopaedic Postoperative Pain Management Total Knee Arthroplasty Continuous Adductor Canal Block Fast Track

ClinConnect Summary

This clinical trial is studying a pain management technique called Continuous Adductor Canal Block (CACB) for patients undergoing total knee replacement surgery, which is often done on the same day without an overnight hospital stay. The goal is to see if using this method can provide longer-lasting pain relief, reduce the need for opioid painkillers, and improve the overall recovery experience for patients. Researchers believe that this technique may lead to better pain control with fewer side effects compared to traditional single shot pain relief methods.

To be eligible for the trial, participants must be at least 21 years old and scheduled for a primary knee replacement surgery. They should be in good health, not dependent on alcohol or drugs, and able to understand and cooperate with the treatment plan. Participants will experience a continuous delivery of local anesthetic through a small tube placed near the nerves in the leg, which is expected to help manage pain after surgery. The study will monitor various outcomes, including pain levels, recovery quality, and any side effects from the treatment. This research is important because it may lead to improved recovery methods for a common procedure, ultimately enhancing patients' quality of life.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients undergoing unilateral primary TKA in the fast track setting.
  • Patients older than 21 years of age, with American Society of Anesthesiologists (ASA)
  • Physical status I-III
  • No alcohol or drug dependency
  • Sufficient understand and co-operation about the perineural catheter.
  • Exclusion Criteria:
  • Perioperative complication or discharge delay leading to hospital admission.
  • Chronic opioid use of morphine 30mg equivalent per day for last 2 consecutive weeks.
  • Allergy to the study medications;
  • Coagulopathy and platelet count \< 105/μL;
  • Patients with contraindications to the insertion of an epidural or adductor canal catheter (severe anatomic abnormalities or history of previous surgery at the site of catheter placement).

About Samuel Lunenfeld Research Institute, Mount Sinai Hospital

The Samuel Lunenfeld Research Institute at Mount Sinai Hospital is a leading biomedical research facility dedicated to advancing our understanding of human health and disease. Renowned for its innovative research programs, the institute focuses on areas such as cancer, genetics, and reproductive health, fostering collaboration among top-tier scientists and clinicians. With a commitment to translating research findings into clinical applications, the Samuel Lunenfeld Research Institute plays a pivotal role in the development of novel therapies and interventions, thereby contributing to improved patient outcomes and the advancement of medical science.

Locations

Toronto, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Naveed Siddiqui, MD

Principal Investigator

Associate Professor

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported