Sleep Length and Euploid Embryo Transfer Prospective Study

Launched by NORTHWESTERN UNIVERSITY · Nov 15, 2023

Keywords

ClinConnect Summary

The SLEEP Study is researching how sleep affects women's fertility, specifically during the process of in vitro fertilization (IVF). Researchers want to understand if getting better sleep can improve the chances of a successful embryo transfer. To do this, they will have participants wear a small device on their finger that tracks their sleep patterns for several weeks before and after the embryo transfer.

Women who are between the ages of 18 and 44 and are preparing for their first, second, or third frozen embryo transfer may be eligible to join this study. However, those with certain conditions, like polycystic ovary syndrome or a very high body mass index, and those who have had multiple failed transfers or significant uterine surgery, will not be included. Participants will track their sleep and may learn more about how their sleep habits impact their fertility journey. This study could help develop new ways to support women in achieving their pregnancy goals.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Undergoing a single euploid frozen embryo transfer
• • Patient's 1st, 2nd, or 3rd embryo transfer (prior fresh or frozen transfers included)
• Exclusion Criteria:
• • Primary infertility diagnosis of polycystic ovary syndrome
• • BMI \> 40
• • Diagnosis of primary ovarian insufficiency (FSH \> 40)
• • Night work
• • High risk of poor outcomes of fertility treatment \[\> 2 prior miscarriages (women with recurrent pregnancy loss), significant uterine factor infertility \[\>/= 2 myomectomies (open abdominal or laparoscopic) or any non-hystoeroscopic myomectomy entering the endometrial cavity\]
• • Undergoing medical fertility preservation for a significant medical co-morbidity
• • Current cancer diagnosis
• • \> 3 prior failed embryo transfers in attempt for current live birth