Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Jan 12, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at two different types of needles used in a specific procedure called EBUS-TBNA, which helps doctors collect samples from enlarged lymph nodes in the chest to diagnose a condition known as sarcoidosis. The researchers want to find out if using a Franseen-type needle gives better sample quality for diagnosis compared to the standard Menghini-type needle. This study is currently recruiting participants who are adults aged 18 and older, have enlarged lymph nodes on a CT scan, and are suspected of having sarcoidosis.

If you join the trial, you will undergo the EBUS-TBNA procedure, where one of the two types of needles will be used to collect samples from your lymph nodes. This study aims to improve how doctors diagnose sarcoidosis, which can be a complex condition. It’s important to note that patients who cannot provide informed consent or have lymph node issues strongly linked to other diseases like cancer or infections will not be eligible to participate. Your involvement will contribute to understanding which needle type may help improve diagnostic accuracy for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • -Any adult patient aged 18 years or older with enlarged mediastinal and/or hilar lymph nodes
• • (≥10 mm short-axis diameter on a CT scan), suspected as having sarcoidosis based on clinical
• • history, physical exam, and other investigations, and booked for EBUS-TBNA.
• Exclusion Criteria:
• • -Patients that are unable to provide informed consent
• • - Patients with lymphadenopathy strongly suspected to be secondary to other diseases based on
• • clinical history, physical exam, and/or other investigations (e.g., lung cancer, lymphoma,
• • infection).