The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery

Launched by ST. OLAVS HOSPITAL · Feb 13, 2024

Keywords

ClinConnect Summary

This clinical trial is studying whether applying a medication called tranexamic acid (TXA) directly onto surgical wounds can help reduce complications after plastic surgery. These complications can include issues like re-bleeding, infections, or wound ruptures. The study will compare the effects of TXA with a placebo (which is a harmless saline solution) to see if TXA truly makes a difference.

To participate in this trial, patients need to be at least 18 years old and scheduled for a plastic surgery procedure where TXA is typically used. They should be able to understand the study information and give their consent to join. During the surgery, participants will receive a single application of either the TXA or placebo on their wound, but they won’t know which one they received. The trial is currently recruiting participants and aims to gather valuable information about the potential benefits and risks of using TXA in surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patients are eligible to be included in the study only if all of the following criteria apply:
• • 1. They are to undergo a surgical procedure within the field of plastic surgery where the procedure involves use of topical TXA at the participating center.
• • 2. They are over 18 years of age and capable of independently providing informed consent
• • 3. They have received adequate oral and written information about the study and signed the informed-consent form
• Exclusion Criteria:
• • Patients with known allergy to tranexamic acid. Insufficient knowledge of national language or English.