Renal Assessment for Early Detection of Renal Impairment in Systemic Sclerosis and Systemic Lupus Erythematosus Patients

Launched by ASSIUT UNIVERSITY · Feb 27, 2024

Keywords

ClinConnect Summary

This clinical trial is designed to help doctors find early signs of kidney problems in patients with systemic sclerosis (SSc) and systemic lupus erythematosus (SLE). The researchers will look at different tests, including special imaging of the kidneys and blood tests, to see how well these methods can detect kidney issues early on. By studying these tests, they hope to improve the way kidney health is monitored in people with these conditions.

To participate in this trial, you need to be an adult over 18 years old and have a confirmed diagnosis of SSc or SLE based on specific medical guidelines. Unfortunately, people with other autoimmune diseases, certain infections, or serious health issues like diabetes and heart failure won't be eligible. If you join the study, you can expect to undergo some tests that are safe and non-invasive, like imaging and blood tests, to help contribute to valuable research aimed at improving kidney health in these patients. The trial is not yet recruiting participants, so there will be more information available soon for those interested.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Adult (aged above 18 years) SSc patients who fulfilled the 2013 European League Against Rheumatism/American College of Rheumatology (EULAR / ACR) for SSC \[13\] and 1980 ACR criteria \[14\].
• • 2. Adult SLE Patients who fulfilled the 2019 EULAR / ACR classification criteria for systemic lupus erythematosus \[15\]
• Exclusion Criteria:
• • 1. Individuals with other autoimmune diseases.
• • 2. Smoking.
• • 3. Infections as chest infection, hepatitis C, hepatitis B and HIV infection.
• • 4. Tumors as hepatocellular carcinoma.
• • 5. Hypertension, diabetes, heart failure, hepatic diseases, chronic renal failure, intrarenal arteriovenous fistula, obstructive nephropathy and urinary tract obstruction.
• • 6. Contraindication for MRI as implanted metallic devices.