Defining Treatment Outcomes and Genetic Architecture in Idiopathic Toe Walking*

Launched by SHRINERS HOSPITALS FOR CHILDREN · Mar 4, 2024

Keywords

ClinConnect Summary

This clinical trial is studying children who have a condition called Idiopathic Toe Walking (ITW), which means they walk on their toes without a known medical reason. The goal of the trial is to compare two types of treatments: non-operative treatment using casting and surgical treatment. Researchers want to see how well each treatment works by looking at how children walk and how their parents feel about the outcomes. Additionally, the study aims to find out if there are specific genes that might be linked to this condition.

To participate in the trial, children must be between 6 and 18 years old and have a diagnosis of persistent Idiopathic Toe Walking. They should also have certain measurements related to their ankle movement. However, children with autism or any other conditions that could affect their walking due to muscle or nerve issues can't take part in the study. If eligible, participants can expect to receive one of the two treatments and be closely monitored to track their progress. This research is important as it may help improve future treatments for children with ITW.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Diagnosis of Idiopathic Toe Walking Persistent (ITWp)
• • 2. Between the ages of 6-18 years
• • 3. Passive dorsiflexion dorsiflexion with knee extension between -10 plantar flexion - + 5 degrees of dorsiflexion, DiGiovanni defined an isolated gastrocnemius contracture as maximum passive ankle dorsiflexion as \< 5 degrees with the knee in full extension
• Exclusion Criteria:
• • 1. Diagnosis of Autism or autism spectrum disorder
• • 2. Presence of any indicators of trauma, neuromuscular influence or neurogenic influence as identified by using the Toe Walking Tool