Reducing Wound Infections Using Bioelectric Wound Dressings

Launched by ADVENTHEALTH · Mar 13, 2024

Keywords

ClinConnect Summary

This clinical trial is looking at how effective a special type of wound dressing, called Bioelectric wound dressing, is in preventing infections after surgery. Researchers want to compare the results of using this new dressing to the traditional method of cleaning the skin with a solution called chlorhexidine before surgery. The goal is to see if the Bioelectric dressing helps reduce the chances of getting an infection after surgeries like removing a benign polyp or treating colon cancer.

To participate in this trial, patients should be between the ages of 18 and 90 and scheduled for certain types of surgeries, such as laparoscopic surgery, which is less invasive. They must also be able to follow instructions for caring for their dressings and have no active infections before the surgery. Participants can expect to receive either the Bioelectric dressing or the standard care, and they will help researchers understand which method works better at preventing infections. It's an important study that could improve care for many patients undergoing similar procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Elective diverticular, benign polyp, or colon cancer resection
• • 2. Age 18-90 years old
• • 3. All patients must receive some kind of bowel prep (SU- prep, pills, Go-Lytely, milk of magnesia, etc....)
• • 4. Must be off antibiotics for more than 2 weeks before surgery
• • 5. Surgery must be laparoscopic, hand assisted or Robotic
• • 6. Skin will be closed in layers and subcuticular interrupted fashion
• • 7. Just one dose of preoperative antibiotics (Invanz or equivalent if patient is allergic)
• • 8. Patients will have a primary anastomosis, no colostomy.
• • 9. Patient must be compliant with dressing care
• • 10. Ability to provide informed consent
• Exclusion Criteria:
• • 1. Active infections before surgery -example: Intra-abdominal abscess not drained or actively on antibiotics on the day of surgery, skin infections
• • 2. Inability to take intestinal bowel preparation
• • 3. HgbA1c \>8
• • 4. BMI \>40
• • 5. Immunosuppression
• • 6. Need of steroid stress dose pre-op
• • 7. Patient receiving active chemotherapy
• • 8. Need of stoma (end ostomies after resection protective stoma included)
• • 9. Need of blood transfusion during surgery
• • 10. Use of irrigation with antibiotics or IRRISEPTR during surgery
• • 11. Any standard contraindication to anesthesia and/or surgery
• • 12. Pregnancy or lactating women
• • 13. Inability to provide informed consent
• • 14. Inability to follow instructions for dressing care
• • 15. Sensitivity or allergy to silver or zinc