Effects of Liposomal Encapsulation on Vitamin C Absorption and Metabolism

Launched by NATIONAL YANG MING CHIAO TUNG UNIVERSITY · Apr 12, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how a special form of vitamin C, called liposomal vitamin C, affects the body's ability to absorb and use this important nutrient. Vitamin C is known for helping with various health functions, such as boosting the immune system and assisting in skin health. The researchers want to see if wrapping vitamin C in tiny fatty bubbles (liposomes) can make it more stable and easier for the body to absorb, especially when taking higher doses of vitamin C. This could be particularly beneficial for people who have higher vitamin C needs, like smokers or those with certain health conditions.

To participate in the trial, you need to be an adult between 20 and 60 years old and generally healthy, meaning you should not have serious diseases affecting your heart, liver, or kidneys. Participants will take the liposomal vitamin C and help researchers understand how well it works compared to regular vitamin C supplements. If you're considering joining, it’s important to know that there are some health conditions and medications that could prevent you from being eligible. This study could offer a new way to improve vitamin C intake, which might benefit your overall health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults aged 20-60 years old, without heart, liver, kidney, endocrine or major organic diseases (patient report), and able to fully cooperate with the experiment.
• Exclusion Criteria:
• • 1. Patients with renal insufficiency and dialysis
• • 2. Cancer patients
• • 3. Underweight (BMI≦17) or obese (BMI≧27)
• • 4. Those taking medications for chronic diseases
• • 5. Blood pressure systolic blood pressure ≧ 130 mmHg or diastolic blood pressure ≧ 85 mmHg
• • 6. Fasting blood glucose ≧ 100 mg/dL
• • 7. Fasting triglycerides ≧ 150 mg/dL, total cholesterol ≧ 200 mg/dL
• • 8. Have a history of vitamin C allergy
• • 9. People suffering from mental illness
• • 10. Pregnant and breastfeeding women
• • 11. Patients with hemosiderosis
• • 12. Kidney stone patients
• • 13. People who take vitamin C for a long time should take supplements (at least 200 mg per day for more than one month)