The Predictive and Prognostic Values of the Fibrinogen to Albumin Ratio and C-reactive Protien to Albumin Ratio in Systemic Lupus Erythematosus Patients

Launched by SOHAG UNIVERSITY · May 5, 2024

Keywords

ClinConnect Summary

This clinical trial is looking to find out how well certain blood tests can predict the activity and outlook of systemic lupus erythematosus (SLE), a chronic autoimmune disease. The study will focus on two specific ratios found in the blood: the Fibrinogen to Albumin Ratio (FAR) and the C-reactive Protein to Albumin Ratio (CAR). By understanding how these ratios relate to the disease, researchers hope to identify new ways to monitor and manage SLE more effectively.

To participate in this trial, individuals must be at least 18 years old and have a confirmed diagnosis of SLE based on specific medical guidelines. Participants should not have any other serious infections or autoimmune diseases. If someone joins the study, they can expect to undergo a series of clinical and laboratory tests to gather data. It's important to note that this trial is not yet recruiting participants, meaning it has not started accepting patients at this time.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients diagnosed as SLE according to SLICC 2012 or ACE/EULAR 2017 classification criteria with
• • 1. ≥18 years of age.
• • 2. Complete clinical and laboratory investigations.
• • 3. No concomitant infection, systemic or other autoimmune diseases.
• Exclusion Criteria:
• Patients were excluded from the study if they had any of the following:
• • 1. \<18 years of age,
• • 2. Incomplete clinical data and laboratory indicators.
• • 3. End-stage kidney disease (defned as requiring dialysis, kidney transplantation, or estimated glomerular fltration rate (eGFR)\<15 mL/min/1.73 m2
• 4. Patients with:
• • 1. Acute infectious diseases, HIV infection carriers,
• • 2. Concomitant systemic diseases such as chronic obstructive lung disease, coronary artery disease, cancer, thyroid function disorder, hematological disorders, acute or chronic liver and renal diseases.
• • 3. Patients with had other autoimmune diseases, such as rheumatoid arthritis, systemic sclerosis, or primary Sjogren's syndrome.