Efficacy of Photobiomodulation in the Treatment and Relief of Pain in Recurrent Aphthous Stomatitis
Launched by FEDERAL UNIVERSITY OF RIO GRANDE DO SUL · May 15, 2024
Trial Information
Current as of February 19, 2025
Not yet recruiting
Keywords
ClinConnect Summary
Recurrent aphthous stomatitis (RAS) is the most common chronic ulcerative inflammatory disorder of the oral cavity, affecting approximately 20% of the general population, with no gender predilection. Its etiopathogenesis remains undefined, although factors such as local trauma and syndromes like Behcet's syndrome are implicated in predisposition. RAS manifests in three distinct clinical presentations, with the smallest being the most common, accounting for 80% of cases. Minor RAS present as round or oval ulcers, smaller than 1 cm, covered by a grayish-white pseudomembrane, commonly occurrin...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients over the age of 18
- • Patients presenting at least one painful mouth ulcer (minor ulcer), located on the tongue, jugal mucosa or labial mucosa, starting on the same day or the day before.
- Exclusion Criteria:
- • Patients who have already undergone other treatment for RAS;
- • Patients with asymptomatic ulcers;
- • Patient must not be undergoing or have undergone any treatment for RAS;
- • Patients with any systemic condition related to RAS - e.g. Behcet's Syndrome, Periodic Fever Syndrome, Pharyngitis and Cervical Adenitis, HIV infection.
Trial Officials
Manoela Martins, PhD
Study Director
Federal University of Rio Grande do Sul
About Federal University Of Rio Grande Do Sul
The Federal University of Rio Grande do Sul (UFRGS) is a leading academic institution in Brazil, renowned for its commitment to research and innovation in various fields, including health sciences. As a prominent clinical trial sponsor, UFRGS leverages its extensive network of researchers and state-of-the-art facilities to advance medical knowledge and improve patient outcomes. The university is dedicated to conducting rigorous and ethically sound clinical studies, fostering collaborations with healthcare professionals, industry partners, and regulatory bodies to ensure the highest standards of scientific integrity and public health impact.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0