Prospective Study on Febrile Batteries in Pediatric Oncohaematological Patients (SuBiTo)
Launched by ASSOCIAZIONE ITALIANA EMATOLOGIA ONCOLOGIA PEDIATRICA · May 16, 2024
Trial Information
Current as of February 19, 2025
Active, not recruiting
Keywords
ClinConnect Summary
Bacterial infections are the most frequent cause of infectious morbidity and mortality in the patient undergoing chemotherapy or hemopoietic stem cell transplantation (TCSE). The main predisposing factor is the impairment of innate immunity as a result of the alteration of mucous barriers (mucositis/enteritis from chemotherapy or radiotherapy), skin (CVC) and neutropenia (non-specific haematological toxicity due to chemotherapy or radiotherapy on bones with hemopoietic marrow). The most frequent form of infection is represented by fever whose cause remains indeterminate in 60-80% of cases. ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • written informed consent,- onset of fever after chemotherapy or after hemopoietic stem cell transplantation (TCSE),
- • endovenous antibiotic therapy for at least 72 hours for the treatment of the febrile episode.
- • ordinary hospitalization scheme
- • age \< 18
About Associazione Italiana Ematologia Oncologia Pediatrica
The Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) is a leading Italian organization dedicated to advancing research and treatment in pediatric hematology and oncology. Comprising a network of specialized centers and healthcare professionals, AIEOP focuses on improving the diagnosis, management, and outcomes of childhood blood disorders and cancers. Through collaborative clinical trials and innovative research initiatives, AIEOP aims to enhance therapeutic strategies, promote evidence-based practices, and ultimately ensure better health prospects for children affected by these critical conditions. The organization is committed to fostering interdisciplinary partnerships and advancing scientific knowledge in the field to improve the quality of care for young patients.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bolzano, , Italy
Milano, , Italy
Parma, , Italy
Pavia, , Italy
Catania, , Italy
Verona, Italia, Italy
Ancona, , Italy
Bari, , Italy
Bologna, , Italy
Brescia, , Italy
Cagliari, , Italy
Ferrara, , Italy
Firenze, , Italy
Genova, , Italy
Modena, , Italy
Monza, , Italy
Napoli, , Italy
Padova, , Italy
Palermo, , Italy
Perugia, , Italy
Pescara, , Italy
Roma, , Italy
San Giovanni Rotondo, , Italy
Torino, , Italy
Trieste, , Italy
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0