Efficacy of Glucose in Serratus Anterior Plane Block to Reduce the Occurrence of Chronic Post-mastectomy Pain

Launched by MANSOURA UNIVERSITY · May 30, 2024

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help manage pain after breast cancer surgery, specifically focusing on chronic pain that some women experience following a mastectomy. Researchers want to see if adding glucose to a common pain relief medication called bupivacaine can improve pain control and reduce the chances of developing chronic pain three months after surgery. Participants will be divided into two groups: one will receive the bupivacaine mixed with glucose, while the other will get bupivacaine mixed with saline (a saltwater solution).

To join the trial, women aged 20 to 60 years who are scheduled for a unilateral modified radical mastectomy and have a good overall health status (as determined by a scoring system) may be eligible. However, women who have certain health issues, such as infections at the injection site or severe kidney or liver diseases, will not be able to participate. If you choose to take part, you can expect to receive the injection before your surgery and will be monitored for any pain following the procedure. This trial aims to help improve pain management options for future patients undergoing similar surgeries.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • American Society of Anesthesiologists physical status I-II
• • age ranging from 20 to 60 years
• • scheduled for unilateral modified radical mastectomy
• Exclusion Criteria:
• • patient refusal to participate in the study
• • infection at site of needle insertion
• • hypersensitivity to the studied drugs
• • psychotic disorders,
• • bilateral MRM ,
• • bleeding disorder
• • chronic renal or hepatic diseases