Clinical Efficacy of Self-adhesive Silicone Gel Waterproof Dressings Versus Conventional Dressings in the Healing of Incisions After Total Joint Arthroplasty

Launched by FIRST AFFILIATED HOSPITAL OF XINJIANG MEDICAL UNIVERSITY · Jun 15, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how effective self-adhesive silicone gel waterproof dressings are compared to traditional gauze dressings for healing after total joint replacement surgery (also known as total joint arthroplasty). The goal is to find out if one type of dressing helps patients heal better and reduce the risk of infections or the need for additional surgery. To participate, individuals need to be at least 18 years old and be undergoing their first joint replacement surgery. However, those with certain health issues, such as severe infections or allergies to the silicone dressings, cannot take part.

Participants in this trial will be randomly assigned to receive either the silicone gel dressing or the conventional gauze dressing after their surgery. Researchers will monitor their healing progress over one year, checking for signs of infection and measuring how well their skin is healing. This study aims to provide valuable information that could help improve patient care and recovery after joint surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥18 years old, gender is not limited;
• • 2. Meet the diagnostic criteria for artificial joint replacement;
• • 3. Initial joint replacement surgery;
• • 4. Voluntary and signed informed consent.
• Exclusion Criteria:
• • 1. Allergic to self-adhesive silicone rubber waterproof dressing;
• • 2. Patients with severe knee joint infection who cannot undergo artificial joint replacement;
• • 3. Progressive renal insufficiency (stage 4 and above) or glomerular filtration rate less than 30ml/min;
• • 4. periprosthesis infection after multiple joint replacement;
• • 5. Active infection at the site of intravenous or joint injection;
• • 6. long-term use of anticoagulants or antiplatelet drugs due to other diseases;
• • 7. Have sepsis or positive blood culture within the last 30 days;
• • 8. Radiotherapy and chemotherapy are required due to neoplastic diseases;
• • 9. Receiving systemic glucocorticoid therapy (prednisone \> 10mg/ day or equivalent hormone medication);
• • 10. severe immunodeficiency diseases (such as stage 3 HIV, sickle cell anemia, splenectomy, etc.);
• • 11. Have a history of drug abuse;
• • 12. Treatment of bone marrow or other transplants with immunosuppressive drugs;
• • 13. Pregnant, parturient and lactating women;
• • 14. Participating in other clinical trials;
• • 15. Researchers believe that other reasons are not appropriate for clinical trial participants.