Effects of Aerobic Exercise on Cancer-Related Biomarkers, Functional Capacity, Cognitive Status and Quality of Life in Women With Breast Cancer

Launched by HASAN KALYONCU UNIVERSITY · Aug 2, 2024

Keywords

ClinConnect Summary

This study is exploring whether exercise can help women who have survived breast cancer feel better and function better. It compares three groups over 12 weeks: (1) moderate‑intensity aerobic exercise three times a week, (2) personalized physical activity counseling to help you stay active, and (3) no new exercise (usual daily activities). Researchers will look at quality of life, how far you can walk in six minutes (a measure of physical fitness), and thinking/cognitive function, plus several blood markers related to inflammation and metabolism. Assessments are planned at the start, at 6 weeks, and at 12 weeks.

To be eligible, you’d need to be a woman aged 18–65 with stage 2 breast cancer who finished primary treatment at least six months ago (not on hormone therapy), be able to read, and be willing to participate. Exclusions include metastasis, a history of lymphedema, certain health conditions, pregnancy, or certain medications. The study is based at Hasan Kalyoncu University in Ankara, Turkey and is currently enrolling about 69 participants. Results aren’t available yet, but the trial aims to show whether exercise or counseling can improve quality of life, physical ability, and possibly inflammatory and metabolic biomarkers in breast cancer survivors.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Patients aged between 18 and 65
• • Literate
• • Diagnosed with stage 2 breast cancer
• • Completed primary breast cancer treatment at least 6 months ago (excluding hormone therapy/aromatase inhibitors)
• • Provided cooperation
• • Female
• • Patients who are willing and willing to participate in the study
• Exclusion Criteria:
• • Those who are using psychotic, anxiolytic, antidepressant, analgesic and sleeping pills
• • Those with metastasis
• • Those with a history of lymphedema
• • Those with neurological disease
• • Those who are pregnant or breastfeeding
• • Uncontrolled hypertensive patients
• • Those who are incapable of verbal communication or physical movement