Age-related Changes in Retinal Oxygen Extraction in Healthy Subjects

Launched by MEDICAL UNIVERSITY OF VIENNA · Oct 14, 2024

Keywords

ClinConnect Summary

This clinical trial is studying how the ability of the eyes to extract oxygen changes as people age. Researchers want to understand if healthy individuals of different ages have different levels of retinal oxygen extraction, which is important because problems with this process can be linked to various eye and health conditions. The study will also look at how breathing pure oxygen for a short time affects the eyes' metabolism. To gather this information, the researchers will use special tools to measure blood flow and oxygen levels in the retina, which is the light-sensitive layer at the back of the eye.

To participate in this study, you need to be a healthy adult between 18 and 80 years old, and you should not smoke or have any significant health issues. Both men and women can join, but you should not have participated in another clinical trial in the past three weeks or have any recent health concerns. If you decide to join, you will be asked to sign a consent form and undergo some non-invasive tests to help researchers learn more about how aging affects the eyes. This trial is currently recruiting participants, and your involvement could contribute valuable insights into eye health as we age.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Men and women aged between 18 and 80 years
• • Signed informed consent
• • Normal ophthalmic findings, unless the investigator considers an abnormality to be clinically irrelevant for the purpose of the study
• • Normal findings in the medical history, unless the investigator considers an abnormality to be clinically irrelevant for the purpose of the study
• • Nonsmokers
• Exclusion Criteria:
• • Abuse of alcoholic beverages or drugs
• • Participation in a clinical trial in the 3 weeks preceding the study
• • Symptoms of a clinically relevant illness in the 3 weeks before the first study day
• • Blood donation during the previous 3 weeks
• • Pregnant or breast-feeding women