Autistic Symptomatology and Sensory Profile in Children with Prader-Willi Syndrome

Launched by UNIVERSITY HOSPITAL, TOULOUSE · Mar 10, 2025

Keywords

ClinConnect Summary

The CASSPER study is a research trial that aims to better understand how children with Prader-Willi Syndrome (PWS) experience autism-like symptoms and sensory issues. PWS is a rare genetic condition that can affect behavior, social interactions, and eating habits. The study will look closely at these autistic traits and sensory profiles in children with PWS and explore whether early treatment with a hormone called oxytocin can help improve these challenges.

To participate in this study, children must be between 3 and 16 years old, have a confirmed diagnosis of PWS with a specific genetic subtype, and be scheduled for a hospital visit or consultation at one of the research centers. Families will need to agree to participate, and there are some conditions that could prevent a child from joining, such as recent changes in medication. This study is not yet recruiting participants, but it aims to provide valuable insights that could lead to better support and interventions for children with PWS in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Child with genetically confirmed PWS and identification of genetic subtype;
• • Child aged between 3 and 16 years;
• • Hospitalisation or multidisciplinary consultation planned for the child's routine follow-up at one of the investigating centres;
• • No parental/legal guardian objection.
• Exclusion Criteria:
• • Change in psychotropic treatment (start, change in dose or discontinuation) in the past 3 months;
• • Inability to provide clear information to parents/legal guardian;
• • Not covered by social security.