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Search / Trial NCT06894667

The Effect of an Antioxidant Gel Compared to Chlorhexidine Gel During the Soft Tissue Healing Process: A Randomized Controlled Clinical Trial

Launched by KUWAIT UNIVERSITY · Mar 19, 2025

Trial Information

Current as of April 23, 2025

Active, not recruiting

Keywords

Antioxidant Scaling And Root Planing

ClinConnect Summary

Background

Periodontitis is characterised by inflammation that results in the loss of periodontal attachment. Scaling and root planing (SRP) is a fundamental non-surgical treatment for periodontitis, which aims to remove the primary causative agents - dental plaque and calculus, from the tooth surfaces. Postoperative care is critical to ensure optimal healing and to manage potential inflammation and microbial load. Traditionally, chlorhexidine, an antimicrobial agent, has been utilized as an adjunctive treatment to prevent infection and manage inflammation following SRP. Chlorhexidine's br...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with Stage 3 or 4 periodontitis would be invited to participate in this study.
  • The following parameters will be used for the diagnosis of periodontitis: (a) presence of bleeding on gentle probing; (b)probing depth (PD) \>6mm; and (c) marginal bone loss (MBL) of at least 3.
  • Exclusion Criteria:
  • Patients will be excluded from the study if they present with gingivitis alone, are currently using oral contraceptives, have systemic conditions such as diabetes or cancer, or are smokers (including those who quit within the past 6 months).
  • Recent antibiotic use within the last 3 months, NSAID or bisphosphonate use within the last 90 days, and any use of chlorhexidine in the past 6 months.

About Kuwait University

Kuwait University is a leading institution dedicated to advancing medical research and education in the region. As a clinical trial sponsor, the university leverages its extensive academic resources and expertise to conduct innovative research aimed at improving healthcare outcomes. Committed to ethical standards and rigorous scientific methodology, Kuwait University collaborates with a diverse range of stakeholders, including researchers, healthcare professionals, and industry partners, to facilitate cutting-edge clinical trials that address pressing health challenges. Through its initiatives, the university aims to contribute significantly to the body of medical knowledge and enhance the quality of patient care in Kuwait and beyond.

Locations

Kuwait City, , Kuwait

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported