The Effect of an Antioxidant Gel Compared to Chlorhexidine Gel During the Soft Tissue Healing Process: A Randomized Controlled Clinical Trial
Launched by KUWAIT UNIVERSITY · Mar 19, 2025
Trial Information
Current as of April 23, 2025
Active, not recruiting
Keywords
ClinConnect Summary
Background
Periodontitis is characterised by inflammation that results in the loss of periodontal attachment. Scaling and root planing (SRP) is a fundamental non-surgical treatment for periodontitis, which aims to remove the primary causative agents - dental plaque and calculus, from the tooth surfaces. Postoperative care is critical to ensure optimal healing and to manage potential inflammation and microbial load. Traditionally, chlorhexidine, an antimicrobial agent, has been utilized as an adjunctive treatment to prevent infection and manage inflammation following SRP. Chlorhexidine's br...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with Stage 3 or 4 periodontitis would be invited to participate in this study.
- • The following parameters will be used for the diagnosis of periodontitis: (a) presence of bleeding on gentle probing; (b)probing depth (PD) \>6mm; and (c) marginal bone loss (MBL) of at least 3.
- Exclusion Criteria:
- • Patients will be excluded from the study if they present with gingivitis alone, are currently using oral contraceptives, have systemic conditions such as diabetes or cancer, or are smokers (including those who quit within the past 6 months).
- • Recent antibiotic use within the last 3 months, NSAID or bisphosphonate use within the last 90 days, and any use of chlorhexidine in the past 6 months.
About Kuwait University
Kuwait University is a leading institution dedicated to advancing medical research and education in the region. As a clinical trial sponsor, the university leverages its extensive academic resources and expertise to conduct innovative research aimed at improving healthcare outcomes. Committed to ethical standards and rigorous scientific methodology, Kuwait University collaborates with a diverse range of stakeholders, including researchers, healthcare professionals, and industry partners, to facilitate cutting-edge clinical trials that address pressing health challenges. Through its initiatives, the university aims to contribute significantly to the body of medical knowledge and enhance the quality of patient care in Kuwait and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Kuwait City, , Kuwait
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported