Tubeless Tracheal and Carinal Reconstruction

Launched by SHUBEN LI · Jul 4, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to perform surgery on the windpipe (trachea) and the area where it splits into the lungs (carina). Usually, patients are put on a breathing machine with a tube during these surgeries, but this study is looking at whether doing the surgery without that breathing tube (called non-intubated anesthesia) is just as safe and may have some benefits during and after the operation.

Adults between 18 and 80 years old who have airway diseases confirmed by special scans and camera exams of the lungs may be eligible to join. To participate, patients need to be in generally good health without serious heart problems, uncontrolled infections, or other major health issues. If you join, you would receive either the usual surgery with a breathing tube or the new approach without it, and the doctors will carefully watch how you do during and after surgery to see which method works better. This trial is currently looking for volunteers who meet these criteria.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Airway diseases were diagnosed by chest enhanced CT and bronchoscopy
• • 2. The patients with age ≥ 18 and ≤ 80 years old
• • 3. ASA (American Society of Anesthesiologists) stage: I-III
• • 4. sign the informed consent. -
• Exclusion Criteria:
• • 1. The patients have proved history of congestive heart failure, angina without good control with medicine; ECG-proved penetrating myocardial infarction; hypertension with bad control; valvulopathy with clinical significance; arrhythmia with high risk and out of control
• • 2. The patients have severe systematic intercurrent disease, such as active infection or poorly controlled diabetes; coagulation disorders; hemorrhagic tendency or under treatment of thrombolysis or anticoagulant therapy
• • 3. Airway anatomical abnormalities due to a history of surgery
• • 4. Patients present with other malignancy