The Mepilex Cesarean Delivery Trial

Launched by MONTEFIORE MEDICAL CENTER · Jul 4, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether a special silver-containing foam dressing called Mepilex Ag can help prevent infections after a cesarean delivery (C-section). Researchers want to find out if this silver dressing lowers the chance of getting an infection at the surgical site compared to the standard dressing usually used after surgery.

Women who are 18 years or older and scheduled for a planned C-section at the study hospital may be eligible to join, as long as they can understand English or Spanish and have a phone for follow-up calls. After the C-section, participants will be randomly given either the silver foam dressing or the regular dressing on their surgical wound. They will then be monitored during the weeks after delivery to check for any signs of infection or wound problems. The trial is not yet recruiting, but it aims to help improve care and recovery for women having C-sections by finding the best way to protect their surgical wounds.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age 18 years or older
• • Undergoing non-emergent cesarean delivery at our institution
• • Able to provide informed consent in English or Spanish
• • Has a working telephone number for follow-up communication
• Exclusion Criteria:
• • Known hypersensitivity or allergy to silver, Aquacel Ag, or adhesive materials
• • Presence of active skin infection or open skin condition at the planned dressing site
• • Participation in another interventional trial affecting wound healing or surgical outcomes
• • Immunocompromised status (e.g., current chemotherapy, chronic steroid use, or known HIV with CD4 \<200)
• • Intraoperative conversion to vertical skin incision or other nonstandard approach
• • Inability to complete follow-up due to anticipated relocation, incarceration, or other logistical barrier