Efficacy Comparison of Itraconazole Pulse Therapy and Terbinafine Therapy in Treatment of Tinea Capitis in Children.

Launched by MUHAMMAD AAMIR LATIF · Jul 7, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two different treatments for tinea capitis, which is a common fungal infection of the scalp in children. The study compares how well itraconazole pulse therapy and terbinafine work to clear this infection. Both medicines are antifungal drugs, but this study aims to see if one is more effective than the other in treating kids with this scalp condition.

Children between the ages of 1 and 13 who have a confirmed diagnosis of tinea capitis (tested positive with a simple lab test called a KOH mount) and have had the infection for more than a month may be eligible to join. Kids who have recently used antifungal treatments or have liver problems are not included. If your child participates, they will receive one of these treatments, and doctors will monitor how well it works and make sure it is safe. This study is currently looking for participants, so if your child fits the criteria, this could be an opportunity to try a treatment that may help clear up their scalp infection.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Any gender
• • Aged 1-13 years
• • With KOH mount positive before start of treatment
• • Duration of disease more than 1 month
• Exclusion Criteria:
• • KOH mount negative before starting the treatment
• • Topical treatment with antifungal agents within past 4 weeks
• • Systemic treatment with antifungal agents within past 4 weeks
• • Patients with active liver disease
• • Patients with elevated liver enzymes