Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study
Launched by RIGSHOSPITALET, DENMARK · Jul 30, 2025
Trial Information
Current as of November 14, 2025
Recruiting
Keywords
ClinConnect Summary
This study is looking at why some people still have moderate to severe pain after hip or knee replacement surgery, even though these surgeries usually work very well. Researchers want to better understand the different types of pain patients might feel, such as nerve-related pain, muscle or joint pain, or pain caused by changes in the nervous system. By studying about 100 patients who continue to have pain months after their surgery, the team hopes to learn more about how common these pain types are and how they overlap. This information could help doctors create better pain treatments before and after surgery.
If you are a patient who has had a hip or knee replacement and still experience moderate to severe pain (rated above 3 on a pain scale), you might be eligible to join this study, unless you have had certain complications like infection or a need for another surgery. Participants will be asked to complete some questionnaires that help identify the kind of pain they have. Taking part means helping researchers understand persistent pain better, which could lead to improved care for future patients. The study is currently recruiting adults of all genders who meet these criteria.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • All patients with persistent moderate-severe pain (NRS\>3) after THA, TKA and UKA
- • Acceptance to be contacted.
- Exclusion Criteria:
- • Re-operation
- • Luxation
- • Do not want to be contacted
- • Post-operative complications such as prosthesis infection, thromboembolism or fracture of the prosthesis.
About Rigshospitalet, Denmark
Rigshospitalet, located in Copenhagen, Denmark, is one of the leading hospitals in Scandinavia and a prominent center for clinical research and innovation. As a key academic institution affiliated with the University of Copenhagen, Rigshospitalet is dedicated to advancing healthcare through rigorous clinical trials and groundbreaking research across various medical disciplines. The hospital’s commitment to excellence is reflected in its multidisciplinary approach, collaboration with international research networks, and focus on improving patient outcomes through evidence-based practices. With state-of-the-art facilities and a team of highly qualified professionals, Rigshospitalet plays a crucial role in translating scientific discoveries into effective treatments and therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
østerbro, Denmark
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported