Incidence of Depression and Its Complications After Surgical Site Infection - ISODEP.

Launched by UNIVERSITY HOSPITAL, BORDEAUX · Aug 8, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how often depression and related problems like poor nutrition happen in people who develop infections at the site of their surgery after orthopedic operations on their limbs or spine. Surgical site infections can be serious and affect a patient’s overall well-being, so the study aims to better understand these mental health and nutrition issues to improve care and prevention for future patients.

Adults over 18 who have had surgery on their arms, legs, or spine—such as joint replacement, spinal surgery, or bone repair—and then developed an infection at the surgery site may be eligible to join. However, people with a history of depression, very low body weight, certain ongoing illnesses, or those who cannot give their consent won’t be included. Participants will be followed to see if depression or malnutrition develops after their infection, helping doctors find better ways to support patients recovering from these complications. The study is not yet recruiting but will include adults of all genders aged 65 to 74.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient \>18 years old
• * Patient treated in infectiology for surgical site infection after orthopedic surgery of the limbs or spine:
• • Prosthetic limb surgery
• • Spinal surgery
• • Traumatology: Osteosynthesis of peripheral limbs or spine
• Exclusion Criteria:
• • Patient under guardianship or curatorship,
• • Pregnant, breastfeeding woman
• • Person deprived of liberty by judicial or administrative decision,
• • Person undergoing psychiatric treatment under duress requiring the consent of the legal representative.
• • Person unable to express their consent,
• • Person under legal protection,
• • Patient not affiliated to a social protection scheme.
• • Patient with a history of diagnosed depression, hospitalization for depressive disorders or taking mood-regulating treatments.
• • An initial BMI of less than \< 18.5, the existence a cancerous pathology, an ongoing inflammatory disease, a pathology responsible for chronic undernutrition