Cardiac Magnetic Resonance - PROgnostic HEart Scar for Sudden Cardiac Death Prediction StudY

Launched by BEIJING ANZHEN HOSPITAL · Aug 15, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether a special type of heart scan called cardiac magnetic resonance (CMR) can help predict the risk of sudden cardiac death in people who have had a heart attack (also called a myocardial infarction). The researchers want to see if the amount and type of scar tissue in the heart, seen on these scans, are linked to the chance of sudden death outside the hospital. They also aim to create a tool that combines scan results with other health information to better identify who might be at higher risk.

People eligible for this study are adults between 18 and 80 years old who had a heart attack and then received a CMR scan at least one month later while their condition was stable. The study does not include those who already have certain heart devices like defibrillators implanted before their heart attack, or those with other serious heart conditions or illnesses expected to limit life to less than a year. Participants will have their health monitored through regular clinic visits and phone calls to track outcomes. This study is currently recruiting and welcomes people of all genders who meet the criteria.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age between 18 and 80 years.
• • 2. Completion of cardiac magnetic resonance (CMR) imaging at Anzhen Hospital during the stable phase (≥1 month) following an acute myocardial infarction (MI).
• Exclusion Criteria:
• • 1. Prior implantation of an implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) before the index MI.
• • 2. Pre-existing diagnosis of a primary arrhythmia syndrome (e.g., long QT syndrome, Brugada syndrome) before the index MI.
• • 3. Concurrent end-stage disease (e.g., advanced malignancy) directly resulting in an estimated life expectancy of less than one year.
• • 4. History of established non-ischemic cardiomyopathy (e.g., dilated, hypertrophic, or restrictive cardiomyopathy) before the index MI.
• • 5. Significant concomitant valvular heart disease. Status post mechanical heart valve replacement.
• • 6. Patients refuse to be followed up.