Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy

Launched by GAZIOSMANPASA RESEARCH AND EDUCATION HOSPITAL · Aug 16, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how different body positions during a kidney stone removal surgery called percutaneous nephrolithotomy (PCNL) affect the patient’s heart and blood flow. During this surgery, patients lie either face down (prone position) or on their back (supine position). The study aims to find out which position helps keep blood pressure and heart function more stable during the operation, which is especially important for patients who might have heart or circulation concerns.

Adults who are generally healthy to moderately ill (based on specific health scores) and have kidney stones needing PCNL may be eligible to join. People with severe heart, lung, or brain problems, infections, or certain other health issues would not qualify. If you participate, you will be randomly assigned to have the surgery in either the prone or supine position, and the medical team will carefully monitor your heart and blood flow throughout. The results of this study could help doctors choose the safest position for kidney stone surgery in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ASA physical status I-III
• • Presence of renal calculi indicated for PNL
• Exclusion Criteria:
• • Pregnancy
• • Uncontrolled coagulopathy
• • Previous renal surgery
• • Severe cardiac, pulmonary, or neurological disease
• • Preoperative urinary tract infection (non-sterile urine culture)
• • Surgery duration \<60 minutes or \>120 minutes
• • Preoperative blood transfusion
• • Multiple access tracts