BCMA/CD3 Bispecific Antibody Treatment for Newly Diagnosed Amyloidosis
Launched by INSTITUTE OF HEMATOLOGY & BLOOD DISEASES HOSPITAL, CHINA ·
Trial Information
Current as of November 14, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new treatment for people who have just been diagnosed with systemic light chain (AL) amyloidosis, a condition where abnormal proteins build up in the body’s organs and tissues. The treatment being tested is called a BCMA/CD3 bispecific antibody (CM336), which is a type of medicine designed to help the immune system target and remove these harmful proteins. The goal of the study is to see how well this low-dose treatment works and to make sure it is safe for patients.
The trial is open to adults aged 65 to 74, regardless of gender, who have recently been diagnosed with this condition. If you join the study, you will receive the new treatment and be closely monitored by doctors at a single medical center. Since this is an early phase study, the focus will be on understanding how the treatment affects your health and whether there are any side effects. It’s important to know that the study is not yet recruiting participants, but it may offer a promising option for those looking for new ways to manage AL amyloidosis.
Gender
ALL
Eligibility criteria
About Institute Of Hematology & Blood Diseases Hospital, China
The Institute of Hematology & Blood Diseases Hospital in China is a leading clinical research institution specializing in hematology and related disorders. Renowned for its commitment to advancing medical knowledge and improving patient care, the Institute conducts innovative clinical trials aimed at developing novel therapies and treatment protocols. With a multidisciplinary team of experts, state-of-the-art facilities, and a robust ethical framework, the Institute is dedicated to enhancing the understanding and management of blood diseases, contributing significantly to global hematological research and patient outcomes.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported