Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

NCT ID: NCT05589714

The Universal Rare Gene Study is a research project aimed at understanding rare genetic causes of retinal dystrophies, like inherited retinal degeneration and retinitis pigmentosa. This internation...

Recruiting

Conditions: Retinitis Pigmentosa, Inherited Retinal Degeneration

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

NCT ID: NCT05773274

The NET RETREAT Trial is a clinical study aimed at comparing two different treatments for patients with metastatic midgut neuroendocrine tumors (NET) that cannot be surgically removed. The trial is...

Recruiting

Phase: PHASE2 Conditions: Metastatic Digestive System Neuroendocrine Tumor G1, Unresectable Digestive System Neuroendocrine Tumor G1 +2 more

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

NCT ID: NCT05835310

This clinical trial is studying a medication called Anifrolumab, which is given through an intravenous (IV) line, to see how well it works and how safe it is for treating children with a condition ...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT ID: NCT05843643

This clinical trial is studying the safety and effectiveness of a medication called upadacitinib for adults with moderate to severe systemic lupus erythematosus (SLE), a disease that causes inflamm...

Recruiting

Phase: PHASE3 Conditions: Systemic Lupus Erythematosus

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

NCT ID: NCT05889182

This clinical trial is studying a medication called upadacitinib to see how effective and safe it is for treating moderate to severe hidradenitis suppurativa (HS) in adults and adolescents who have...

Recruiting

Phase: PHASE3 Conditions: Hidradenitis Suppurativa

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

NCT ID: NCT06337318

This clinical trial is looking at two different treatments for people with a type of cancer called follicular lymphoma, specifically for those who have a low amount of tumor present. The two treatm...

Recruiting

Phase: PHASE3 Conditions: Classic Follicular Lymphoma, Follicular Lymphoma With Unusual Cytological Features

Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma

NCT ID: NCT06356129

This clinical trial is studying a new treatment for patients with a type of cancer called high-risk large B-cell lymphoma (LBCL). Researchers want to see if adding a medication called golcadomide t...

Recruiting

Phase: PHASE3 Conditions: Large B-cell Lymphoma

Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

NCT ID: NCT06465316

This clinical trial is studying a new treatment approach for patients with relapsed or refractory multiple myeloma, a type of blood cancer that keeps coming back or does not respond to existing tre...

Recruiting

Phase: PHASE1 Conditions: Refractory Multiple Myeloma, Recurrent Multiple Myeloma

US National TOP Registry

NCT ID: NCT06513091

The US National TOP Registry is a clinical study aimed at understanding how well donor lungs perform after being preserved and evaluated using a special device called the OCS Lung System. This stud...

Recruiting

Conditions: Lung Transplant

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

NCT ID: NCT06541704

This clinical trial is looking at two study drugs, pozelimab and cemdisiran, to see how well they can slow down the progression of geographic atrophy (GA), a serious eye condition caused by age-rel...

Recruiting

Phase: PHASE3 Conditions: Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

NCT ID: NCT06564818

This clinical trial is studying a new treatment called CYB003, which is a type of psilocybin analog, for people with Major Depressive Disorder (MDD). The goal of the study is to see if CYB003 is ef...

Recruiting

Phase: PHASE3 Conditions: Major Depressive Disorder

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

NCT ID: NCT06585787

The ADEPT-4 clinical trial is studying a new treatment called KarXT for individuals with Alzheimer's Disease (AD) who are experiencing psychosis, which includes symptoms like hallucinations or delu...

Recruiting

Phase: PHASE3 Conditions: Alzheimer Disease

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

NCT ID: NCT06661720

This clinical trial is studying whether adding a drug called tivozanib to the standard treatment, pembrolizumab, can improve outcomes for patients with certain types of kidney cancer, specifically ...

Recruiting

Phase: PHASE3 Conditions: Clear Cell Renal Cell Carcinoma, Renal Cell Carcinoma (RCC) +2 more

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

NCT ID: NCT06722157

This clinical trial is investigating a new treatment called BI 771716 for people aged 50 and older who have an advanced eye condition known as geographic atrophy, which is a type of age-related mac...

Recruiting

Phase: PHASE2 Conditions: Geographic Atrophy, Macular Degeneration, Age-related

The AIRTIVITY® Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

NCT ID: NCT06872892

The AIRTIVITY® Study is a clinical trial that aims to find out if a medication called BI 1291583 can help adults with bronchiectasis, a condition that affects the lungs and often leads to coughing ...

Recruiting

Phase: PHASE3 Conditions: Bronchiectasis

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

NCT ID: NCT07000123

This clinical trial is studying a new medication called AZD0780, which is designed to lower levels of LDL cholesterol (often referred to as "bad" cholesterol) in the blood. The trial is for adults ...

Recruiting

Phase: PHASE3 Conditions: Cardiovascular Disease

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

NCT ID: NCT07064473

This clinical trial is studying whether a new medicine called vicadrostat, when taken together with an existing diabetes medicine called empagliflozin, can help lower the risk of heart problems in ...

Recruiting

Phase: PHASE3 Conditions: Hypertension, Diabetes Mellitus, Type 2 +1 more

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

NCT ID: NCT07107945

This clinical trial is studying whether a medicine called empagliflozin can help children and teenagers aged 2 to 17 who have chronic kidney disease (CKD), a condition where the kidneys do not work...

Not yet recruiting

Phase: PHASE3 Conditions: Chronic Kidney Disease

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

NCT ID: NCT04929223

The INTRINSIC trial is studying how safe and effective certain targeted therapies or immunotherapies are for patients with metastatic colorectal cancer (mCRC). This means they are looking at treatm...

Recruiting

Phase: PHASE1 Conditions: Metastatic Colorectal Cancer

A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting

NCT ID: NCT05348733

The FINE-REAL study is looking at how well the medication finerenone works for people with chronic kidney disease (CKD) and type 2 diabetes (T2D) when prescribed by their doctors in everyday medica...

Recruiting

Conditions: Type 2 Diabetes Mellitus, Chronic Kidney Disease

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Clinical Trials in Phoenix, Arizona

969 Active Trials Found in Phoenix

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Study to Compare the Effectiveness and Safety of Golcadomide Plus R-CHOP vs Placebo Plus R-CHOP in Participants With Previously Untreated High-risk Large B-cell Lymphoma

Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

US National TOP Registry

A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

A Study to Test Whether BI 771716 Helps People With an Advanced Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

The AIRTIVITY® Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting