A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

NCT ID: NCT06077760

This clinical trial is looking at a new treatment combination for patients with non-small cell lung cancer (NSCLC) who have had surgery to remove their cancer. The study compares the effects of a d...

Recruiting

Phase: PHASE3 Conditions: Non-small Cell Lung Cancer

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

NCT ID: NCT06136559

This clinical trial is studying a new medication called nemtabrutinib (MK-1026) to see how it compares to two existing treatments, ibrutinib and acalabrutinib, for patients with chronic lymphocytic...

Recruiting

Phase: PHASE3 Conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma

A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant, Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004)

NCT ID: NCT06345729

This clinical trial is investigating a new combination treatment for patients with a specific type of advanced lung cancer known as non-small cell lung cancer (NSCLC). Participants in this study wi...

Recruiting

Phase: PHASE3 Conditions: Non-small Cell Lung Cancer

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

NCT ID: NCT06430801

This clinical trial is studying a new medication called tulisokibart, which is being tested for its effectiveness and safety in treating people with moderate to severe Crohn's disease. Crohn's dise...

Recruiting

Phase: PHASE3 Conditions: Crohn's Disease

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

NCT ID: NCT06623422

This clinical trial is studying whether a combination of two treatments, pembrolizumab and V940, can help people with non-small cell lung cancer (NSCLC) stay cancer-free for a longer time after sur...

Recruiting

Phase: PHASE3 Conditions: Carcinoma, Non-Small-Cell Lung

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

NCT ID: NCT03645928

This clinical trial is studying a new type of treatment called adoptive cell therapy (ACT) that uses the body's own immune cells to fight certain types of cancer, specifically metastatic melanoma, ...

Recruiting

Phase: PHASE2 Conditions: Non-small Cell Lung Cancer, Metastatic Melanoma +1 more

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

NCT ID: NCT03486873

This clinical trial, called MK-3475-587, is looking into the long-term safety and effectiveness of a treatment called pembrolizumab (also known as MK-3475) for patients with advanced tumors. If you...

Recruiting

Phase: PHASE3 Conditions: Solid Tumors, Hematologic Malignancies

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

NCT ID: NCT05636176

This clinical trial is studying a new treatment called ziltivekimab for people with heart failure who also have inflammation. Heart failure means the heart isn't pumping blood as well as it should,...

Recruiting

Phase: PHASE3 Conditions: Heart Failure

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

NCT ID: NCT06200207

This clinical trial is studying a new medicine called ziltivekimab to see how well it works for people with heart failure and inflammation. Participants in the study will either receive ziltivekima...

Recruiting

Phase: PHASE3 Conditions: Heart Failure, Systemic Inflammation

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

NCT ID: NCT06312020

This clinical trial is investigating a new treatment called HZN-1116 for people with Sjogren's syndrome, a condition that affects moisture-producing glands and can cause dry mouth and eyes, among o...

Recruiting

Phase: PHASE2 Conditions: Sjogren's Syndrome

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

NCT ID: NCT07011732

The ADAGIO-1 clinical trial is a study looking at a new treatment called KarXT combined with KarX-EC for adults experiencing agitation due to Alzheimer’s disease. Agitation can include feelings of ...

Not yet recruiting

Phase: PHASE3 Conditions: Alzheimer Disease

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

NCT ID: NCT04613596

The KRYSTAL-7 trial is studying a new treatment for patients with advanced non-small cell lung cancer (NSCLC) that has a specific mutation called KRAS G12C. The trial has two parts: the Phase 2 par...

Recruiting

Phase: PHASE2 Conditions: Advanced Non-Small Cell Lung Cancer, Metastatic Non-Small Cell Lung Cancer

Study to Evaluate the Effectiveness of Risankizumab in Participants With a Recent Diagnosis of Moderate Plaque Psoriasis in a Real-life Setting in Greece

NCT ID: NCT06247319

This clinical trial is studying the effectiveness of a medication called risankizumab for people who have recently been diagnosed with moderate plaque psoriasis, a skin condition that causes red, i...

Recruiting

Conditions: Psoriasis, Moderate Plaque Psoriasis +1 more

Electroanatomical Mapping Versus Fluoroscopy Based Pulmonary Vein Isolation by Means of PulseSelect Catheter in Patients With Atrial Fibrillation

NCT ID: NCT07035288

This clinical trial is comparing two ways of treating a heart rhythm problem called atrial fibrillation (AF) using a procedure called pulmonary vein isolation (PVI). One method uses a special mappi...

Recruiting

Phase: NA Conditions: Catheter Ablation, Atrial Fibrillation (AF) +1 more

Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46)

NCT ID: NCT05609968

This clinical trial is studying two different treatment options for adults with metastatic non-small cell lung cancer (NSCLC) that has a specific marker called PD-L1, which is found in at least 50%...

Recruiting

Phase: PHASE3 Conditions: Carcinoma, Non-Small-Cell Lung

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

NCT ID: NCT06717347

This clinical trial is studying a new treatment for patients with diffuse large B-cell lymphoma (DLBCL), a type of cancer that affects the lymphatic system. Researchers want to see if adding a drug...

Recruiting

Phase: PHASE3 Conditions: Diffuse Large B-Cell Lymphoma

Flecainide Versus Amiodarone in the Cardioversion of Paroxysmal Atrial Fibrillation at the Emergency Department, in Patients With Coronary Artery Disease Without Residual Ischemia

NCT ID: NCT05549752

This clinical trial is looking at two medications, flecainide and amiodarone, to see which one works better for treating a heart condition called paroxysmal atrial fibrillation in patients who have...

Recruiting

Phase: PHASE3 Conditions: Atrial Fibrillation Paroxysmal, Coronary Artery Disease Without Residual Ischemia

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

NCT ID: NCT06254950

This clinical trial is studying a new medication called TAK-279 to see if it can help reduce inflammation in the bowels of people with moderately to severely active ulcerative colitis (UC). The mai...

Recruiting

Phase: PHASE2 Conditions: Ulcerative Colitis

A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

NCT ID: NCT05878717

This clinical trial is studying a medication called belimumab to see how well it works and how safe it is for adults with a condition known as systemic sclerosis associated interstitial lung diseas...

Recruiting

Phase: PHASE2 Conditions: Scleroderma, Systemic, Systemic Sclerosis Associated Interstitial Lung Disease

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT ID: NCT06395103

This clinical trial, called Substudy 01A, is investigating a new treatment called zilovertamab vedotin for children and young adults with certain types of blood cancers and solid tumors. Specifical...

Recruiting

Phase: PHASE1 Conditions: Neuroblastoma, Diffuse Large B-cell Lymphoma +3 more

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Clinical Trials in Athens, Attiki

92 Active Trials Found in Athens

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

A Study of MK-1084 Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant, Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004)

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation

A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Study to Evaluate the Effectiveness of Risankizumab in Participants With a Recent Diagnosis of Moderate Plaque Psoriasis in a Real-life Setting in Greece

Electroanatomical Mapping Versus Fluoroscopy Based Pulmonary Vein Isolation by Means of PulseSelect Catheter in Patients With Atrial Fibrillation

Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46)

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Flecainide Versus Amiodarone in the Cardioversion of Paroxysmal Atrial Fibrillation at the Emergency Department, in Patients With Coronary Artery Disease Without Residual Ischemia

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)