Trials
Search / Trial NCT00000168

Longitudinal Study of Ocular Complications of AIDS (LSOCA)

Launched by JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH · Sep 23, 1999

Trial Information

Current as of January 15, 2025

Completed

Keywords

ClinConnect Summary

Ocular abnormalities in patients with AIDS were first reported in 1982. The most common finding is a non-infectious "HIV retinopathy", characterized by cotton wool spots, intraretinal hemorrhages, and/or microaneurysms. These changes occur in approximately 50 percent of patients with AIDS. HIV retinopathy alone is not typically associated with clinical loss of vision, but functional deficits in patients with AIDS without other ocular complications may be due to this phenomenon.

CMV retinitis has had the most clinical importance of all the associated complications of AIDS. It is commonly se...

Gender

ALL

Eligibility criteria

  • Inclusion criteria:
  • A diagnosis of AIDS according to the 1993 Centers for Disease Control and Prevention (CDC) definition (with or without clinical symptoms of CMV retinitis or other ocular complications of AIDS)
  • Age 13 years or older
  • Signed consent statement
  • Patients with newly diagnosed (within 45 days of enrollment) Ocular Opportunistic Infections (OOIs)
  • Patients without a newly diagnosed Ocular Opportunistic Infection (OOI) diagnosed with AIDS after 1 Jan 2001
  • Exclusion criteria:
  • - none.

Trial Officials

Doug A Jabs, MD

Study Chair

Icahn School of Medicine at Mount Sinai

About Johns Hopkins Bloomberg School Of Public Health

The Johns Hopkins Bloomberg School of Public Health is a leading institution dedicated to advancing public health research and education. Renowned for its rigorous academic programs and commitment to improving global health outcomes, the School conducts innovative clinical trials that address pressing health challenges. With a focus on evidence-based practices, multidisciplinary collaboration, and community engagement, the Bloomberg School leverages its extensive resources and expertise to contribute to the development of effective public health interventions and policies. Through its research endeavors, the School aims to enhance population health and inform health policy both locally and globally.

Locations

Los Angeles, California, United States

Baltimore, Maryland, United States

Newark, New Jersey, United States

Chapel Hill, North Carolina, United States

Chicago, Illinois, United States

Irvine, California, United States

La Jolla, California, United States

Los Angeles, California, United States

San Francisco, California, United States

Miami, Florida, United States

Tampa, Florida, United States

Atlanta, Georgia, United States

Indianapolis, Indiana, United States

New Orleans, Louisiana, United States

New York, New York, United States

Philadelphia, Pennsylvania, United States

Galveston, Texas, United States

Houston, Texas, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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