Longitudinal Study of Ocular Complications of AIDS (LSOCA)
Launched by JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH · Sep 23, 1999
Trial Information
Current as of January 15, 2025
Completed
Keywords
ClinConnect Summary
Ocular abnormalities in patients with AIDS were first reported in 1982. The most common finding is a non-infectious "HIV retinopathy", characterized by cotton wool spots, intraretinal hemorrhages, and/or microaneurysms. These changes occur in approximately 50 percent of patients with AIDS. HIV retinopathy alone is not typically associated with clinical loss of vision, but functional deficits in patients with AIDS without other ocular complications may be due to this phenomenon.
CMV retinitis has had the most clinical importance of all the associated complications of AIDS. It is commonly se...
Gender
ALL
Eligibility criteria
- Inclusion criteria:
- • A diagnosis of AIDS according to the 1993 Centers for Disease Control and Prevention (CDC) definition (with or without clinical symptoms of CMV retinitis or other ocular complications of AIDS)
- • Age 13 years or older
- • Signed consent statement
- • Patients with newly diagnosed (within 45 days of enrollment) Ocular Opportunistic Infections (OOIs)
- • Patients without a newly diagnosed Ocular Opportunistic Infection (OOI) diagnosed with AIDS after 1 Jan 2001
- Exclusion criteria:
- • - none.
Trial Officials
Doug A Jabs, MD
Study Chair
Icahn School of Medicine at Mount Sinai
About Johns Hopkins Bloomberg School Of Public Health
The Johns Hopkins Bloomberg School of Public Health is a leading institution dedicated to advancing public health research and education. Renowned for its rigorous academic programs and commitment to improving global health outcomes, the School conducts innovative clinical trials that address pressing health challenges. With a focus on evidence-based practices, multidisciplinary collaboration, and community engagement, the Bloomberg School leverages its extensive resources and expertise to contribute to the development of effective public health interventions and policies. Through its research endeavors, the School aims to enhance population health and inform health policy both locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Los Angeles, California, United States
Baltimore, Maryland, United States
Newark, New Jersey, United States
Chapel Hill, North Carolina, United States
Chicago, Illinois, United States
Irvine, California, United States
La Jolla, California, United States
Los Angeles, California, United States
San Francisco, California, United States
Miami, Florida, United States
Tampa, Florida, United States
Atlanta, Georgia, United States
Indianapolis, Indiana, United States
New Orleans, Louisiana, United States
New York, New York, United States
Philadelphia, Pennsylvania, United States
Galveston, Texas, United States
Houston, Texas, United States
People applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Discussion 0
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