Longitudinal Study of Ocular Complications of AIDS (LSOCA)

Launched by JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH · Sep 23, 1999

Keywords

ClinConnect Summary

Ocular abnormalities in patients with AIDS were first reported in 1982. The most common finding is a non-infectious "HIV retinopathy", characterized by cotton wool spots, intraretinal hemorrhages, and/or microaneurysms. These changes occur in approximately 50 percent of patients with AIDS. HIV retinopathy alone is not typically associated with clinical loss of vision, but functional deficits in patients with AIDS without other ocular complications may be due to this phenomenon.

CMV retinitis has had the most clinical importance of all the associated complications of AIDS. It is commonly se...

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • A diagnosis of AIDS according to the 1993 Centers for Disease Control and Prevention (CDC) definition (with or without clinical symptoms of CMV retinitis or other ocular complications of AIDS)
• • Age 13 years or older
• • Signed consent statement
• • Patients with newly diagnosed (within 45 days of enrollment) Ocular Opportunistic Infections (OOIs)
• • Patients without a newly diagnosed Ocular Opportunistic Infection (OOI) diagnosed with AIDS after 1 Jan 2001
• Exclusion criteria:
• • - none.

Trial Officials