Search / Trial NCT00000168

Longitudinal Study of Ocular Complications of AIDS (LSOCA)

Launched by JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH · Sep 23, 1999

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Trial Information

Current as of September 11, 2024

Completed

Keywords

Description

Ocular abnormalities in patients with AIDS were first reported in 1982. The most common finding is a non-infectious "HIV retinopathy", characterized by cotton wool spots, intraretinal hemorrhages, and/or microaneurysms. These changes occur in approximately 50 percent of patients with AIDS. HIV retinopathy alone is not typically associated with clinical loss of vision, but functional deficits in patients with AIDS without other ocular complications may be due to this phenomenon. CMV retinitis has had the most clinical importance of all the associated complications of AIDS. It is commonly se...

Gender

ALL

Eligibility criteria

  • Inclusion criteria:
  • * A diagnosis of AIDS according to the 1993 Centers for Disease Control and Prevention (CDC) definition (with or without clinical symptoms of CMV retinitis or other ocular complications of AIDS)
  • * Age 13 years or older
  • * Signed consent statement
  • * Patients with newly diagnosed (within 45 days of enrollment) Ocular Opportunistic Infections (OOIs)
  • * Patients without a newly diagnosed Ocular Opportunistic Infection (OOI) diagnosed with AIDS after 1 Jan 2001
  • Exclusion criteria:
  • - none.

About Sponsor

The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

Contacts

JC

Jennifer Cobb

Immunology at National Institute of Allergy and Infectious Diseases (NIAID)

Locations

Los Angeles, California, United States

Baltimore, Maryland, United States

Newark, New Jersey, United States

Chapel Hill, North Carolina, United States

Chicago, Illinois, United States

Irvine, California, United States

La Jolla, California, United States

Los Angeles, California, United States

San Francisco, California, United States

Miami, Florida, United States

Tampa, Florida, United States

Atlanta, Georgia, United States

Indianapolis, Indiana, United States

New Orleans, Louisiana, United States

New York, New York, United States

Philadelphia, Pennsylvania, United States

Galveston, Texas, United States

Houston, Texas, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0