Search / Trial NCT00000170

Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia

Launched by JAEB CENTER FOR HEALTH RESEARCH · Sep 23, 1999

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Trial Information

Current as of March 02, 2024

Completed

Keywords

Amblyopia Patching Atropine

Description

Amblyopia, or lazy eye, is the most common cause of visual impairment in children and often persists in adulthood. It is reported to be the leading cause of vision loss in one eye in the 20-70 year old age group, with a prevalence of 1-4 percent in various studies, indicating that both improved means of detection and treatment are needed. Most of the available data on the natural history of amblyopia and success rates of its treatment with either patching or drug therapy are retrospective and uncontrolled. Despite the common occurrence of amblyopia, there is little quality data on treatmen...

Gender

All

Eligibility criteria

  • Inclusion Criteria:
  • Patients must be 7 years old or younger with amblyopia due to strabismus or anisometropia
  • Visual acuity in the amblyopic eye must be between 20/40 and 20/100
  • Visual acuity in the sound eye or 20/40 or better
  • At least 3 lines of acuity difference between the two eyes
  • Exclusion Criteria:
  • More than two months of amblyopia therapy in the past two years
  • Myopia (more than -0.50 D)

Attachments

readout_NCT00000170_2024-03-02.pdf

4.5 MB

NCT00000170_study_protocol.pdf

4.5 MB

About company

The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

Contacts

JC

Jennifer Cobb

Immunology at National Institute of Allergy and Infectious Diseases (NIAID)

Locations

Baltimore, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

6 months

Reviews (48)

4.6

All reviews come from applied patients

5 stars
41
4 stars
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3 stars
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Leslie Alexander
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Michael Foster
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Dries Vincent
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

Leslie Alexander
20 September 2023

Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum?

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