Nctid:
NCT00000212
Payload:
{"hasResults"=>false, "derivedSection"=>{"miscInfoModule"=>{"versionHolder"=>"2024-12-20"}, "conditionBrowseModule"=>{"meshes"=>[{"id"=>"D019970", "term"=>"Cocaine-Related Disorders"}], "ancestors"=>[{"id"=>"D019966", "term"=>"Substance-Related Disorders"}, {"id"=>"D064419", "term"=>"Chemically-Induced Disorders"}, {"id"=>"D001523", "term"=>"Mental Disorders"}], "browseLeaves"=>[{"id"=>"M21841", "name"=>"Cocaine-Related Disorders", "asFound"=>"Cocaine-Related Disorders", "relevance"=>"HIGH"}, {"id"=>"M21837", "name"=>"Substance-Related Disorders", "relevance"=>"LOW"}, {"id"=>"M30302", "name"=>"Chemically-Induced Disorders", "relevance"=>"LOW"}, {"id"=>"M14473", "name"=>"Psychotic Disorders", "relevance"=>"LOW"}, {"id"=>"M4815", "name"=>"Mental Disorders", "relevance"=>"LOW"}], "browseBranches"=>[{"name"=>"Substance Related Disorders", "abbrev"=>"BC25"}, {"name"=>"Behaviors and Mental Disorders", "abbrev"=>"BXM"}, {"name"=>"All Conditions", "abbrev"=>"All"}]}, "interventionBrowseModule"=>{"meshes"=>[{"id"=>"D003891", "term"=>"Desipramine"}], "ancestors"=>[{"id"=>"D000929", "term"=>"Antidepressive Agents, Tricyclic"}, {"id"=>"D000928", "term"=>"Antidepressive Agents"}, {"id"=>"D011619", "term"=>"Psychotropic Drugs"}, {"id"=>"D004791", "term"=>"Enzyme Inhibitors"}, {"id"=>"D045504", "term"=>"Molecular Mechanisms of Pharmacological Action"}, {"id"=>"D018759", "term"=>"Adrenergic Uptake Inhibitors"}, {"id"=>"D014179", "term"=>"Neurotransmitter Uptake Inhibitors"}, {"id"=>"D049990", "term"=>"Membrane Transport Modulators"}, {"id"=>"D018663", "term"=>"Adrenergic Agents"}, {"id"=>"D018377", "term"=>"Neurotransmitter Agents"}, {"id"=>"D045505", "term"=>"Physiological Effects of Drugs"}], "browseLeaves"=>[{"id"=>"M6271", "name"=>"Cocaine", "relevance"=>"LOW"}, {"id"=>"M7086", "name"=>"Desipramine", "asFound"=>"CST", "relevance"=>"HIGH"}, {"id"=>"M4247", "name"=>"Antidepressive Agents", "relevance"=>"LOW"}, {"id"=>"M4248", "name"=>"Antidepressive Agents, Tricyclic", "relevance"=>"LOW"}, {"id"=>"M14474", "name"=>"Psychotropic Drugs", "relevance"=>"LOW"}, {"id"=>"M7951", "name"=>"Enzyme Inhibitors", "relevance"=>"LOW"}, {"id"=>"M20746", "name"=>"Adrenergic Agents", "relevance"=>"LOW"}, {"id"=>"M20504", "name"=>"Neurotransmitter Agents", "relevance"=>"LOW"}], "browseBranches"=>[{"name"=>"Vasoconstrictor Agents", "abbrev"=>"VaCoAg"}, {"name"=>"Central Nervous System Depressants", "abbrev"=>"CNSDep"}, {"name"=>"All Drugs and Chemicals", "abbrev"=>"All"}, {"name"=>"Psychotropic Drugs", "abbrev"=>"PsychDr"}]}}, "protocolSection"=>{"designModule"=>{"phases"=>["PHASE2"], "studyType"=>"INTERVENTIONAL", "designInfo"=>{"primaryPurpose"=>"TREATMENT"}, "enrollmentInfo"=>{"count"=>0}}, "statusModule"=>{"overallStatus"=>"COMPLETED", "startDateStruct"=>{"date"=>"1987-07"}, "expandedAccessInfo"=>{"hasExpandedAccess"=>false}, "statusVerifiedDate"=>"2012-12", "completionDateStruct"=>{"date"=>"1988-07", "type"=>"ACTUAL"}, "lastUpdateSubmitDate"=>"2015-08-27", "studyFirstSubmitDate"=>"1999-09-20", "studyFirstSubmitQcDate"=>"1999-09-20", "lastUpdatePostDateStruct"=>{"date"=>"2015-08-31", "type"=>"ESTIMATED"}, "studyFirstPostDateStruct"=>{"date"=>"1999-09-21", "type"=>"ESTIMATED"}, "primaryCompletionDateStruct"=>{"date"=>"1988-07", "type"=>"ACTUAL"}}, "outcomesModule"=>{"primaryOutcomes"=>[{"measure"=>"Amount cocaine self-administered"}, {"measure"=>"Direct cocaine effects (cardiovascular, subjective"}, {"measure"=>"Interaction of cocaine and DMI on cardio measures"}, {"measure"=>"Interaction of cocaine/DMI on coc's subjective"}, {"measure"=>"Effects of DMI on cocaine craving"}, {"measure"=>"Drug use during outpatient DMI maintenance"}]}, "conditionsModule"=>{"keywords"=>["crack cocaine"], "conditions"=>["Cocaine-Related Disorders"]}, "referencesModule"=>{"references"=>[{"pmid"=>"2338656", "type"=>"BACKGROUND", "citation"=>"Fischman MW, Foltin RW, Nestadt G, Pearlson GD. Effects of desipramine maintenance on cocaine self-administration by humans. J Pharmacol Exp Ther. 1990 May;253(2):760-70."}]}, "descriptionModule"=>{"briefSummary"=>"The purpose of this study is to evaluate the effects of desipramine DMI maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving."}, "eligibilityModule"=>{"sex"=>"ALL", "stdAges"=>["ADULT"], "maximumAge"=>"45 years", "minimumAge"=>"18 years", "healthyVolunteers"=>false, "eligibilityCriteria"=>"Please contact site for information."}, "identificationModule"=>{"nctId"=>"NCT00000212", "briefTitle"=>"IV Cocaine Abuse: A Laboratory Model - 1", "organization"=>{"class"=>"OTHER", "fullName"=>"New York State Psychiatric Institute"}, "officialTitle"=>"IV Cocaine Abuse: A Laboratory Model", "orgStudyIdInfo"=>{"id"=>"NIDA-06234-1"}, "secondaryIdInfos"=>[{"id"=>"R01DA006234", "link"=>"https://reporter.nih.gov/quickSearch/R01DA006234", "type"=>"NIH"}, {"id"=>"R01-06234-1"}]}, "armsInterventionsModule"=>{"interventions"=>[{"name"=>"Desipramine", "type"=>"DRUG"}]}, "contactsLocationsModule"=>{"locations"=>[{"zip"=>"10023", "city"=>"New York", "state"=>"New York", "country"=>"United States", "facility"=>"Columbia University", "geoPoint"=>{"lat"=>40.71427, "lon"=>-74.00597}}], "overallOfficials"=>[{"name"=>"Richard Foltin, Ph.D.", "role"=>"PRINCIPAL_INVESTIGATOR", "affiliation"=>"Columbia University"}]}, "sponsorCollaboratorsModule"=>{"leadSponsor"=>{"name"=>"New York State Psychiatric Institute", "class"=>"OTHER"}, "collaborators"=>[{"name"=>"National Institute on Drug Abuse (NIDA)", "class"=>"NIH"}, {"name"=>"Columbia University", "class"=>"OTHER"}], "responsibleParty"=>{"type"=>"SPONSOR"}}}}
