Search / Trial NCT00000374

Treatment for First-Episode Schizophrenia

Launched by NORTHWELL HEALTH · Nov 2, 1999

Trial Information

Current as of November 14, 2024

Completed

Keywords

Adolescence Adult Antipsychotic Agents Female Human Male Olanzapine Risperidone Schizophrenia Antipsychotic Agents *Therapeutic Use Olanzapine *Therapeutic Use Risperidone *Therapeutic Use Schizophrenia *Drug Therapy

ClinConnect Summary

The goal of the study is to prevent morbidity in first-episode schizophrenia using second-generation antipsychotic drugs: olanzapine, risperidone.

Long-term studies of first-episode schizophrenia patients have clearly indicated excellent initial responsiveness of positive psychotic symptoms to treatment with conventional antipsychotic medications. However, in the years immediately following this initial good response, morbidity increases. Relapses, often multiple ones, are the rule and are usually precipitated by medication noncompliance. There is some evidence that the second-generation a...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • First episode schizophrenia, schizophreniform disorder or schizoaffective disorder
  • Exclusion Criteria:
  • Prior treatment with antipsychotic medications.

Trial Officials

Delbert Robinson, MD

Principal Investigator

The Zucker Hillside Hospital

About Northwell Health

Northwell Health is a leading integrated health system based in New York, dedicated to advancing healthcare through innovative research and clinical trials. With a commitment to improving patient outcomes and enhancing medical knowledge, Northwell Health conducts a diverse range of clinical studies across various therapeutic areas. The organization harnesses its extensive network of hospitals, outpatient facilities, and research institutes to facilitate cutting-edge research, ensuring access to advanced treatments for patients while fostering collaboration among healthcare professionals, researchers, and industry partners. By prioritizing patient-centric approaches and leveraging state-of-the-art technology, Northwell Health aims to drive significant advancements in medical science and public health.

Locations

Bronx, New York, United States

Glen Oaks, New York, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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