Bone Estrogen Strength Training

Launched by UNIVERSITY OF ARIZONA · Nov 3, 1999

Keywords

ClinConnect Summary

Osteoporotic fractures associated with low bone mineral density (BMD) are a significant public health problem for women, resulting in over 1 million fractures per year. The increasing incidence of fractures will make an already major health problem an even greater one in the future. Estimates of medical costs for the treatment of osteoporotic fractures are expected to increase from $14.8 billion in 1995 to $60 billion by 2020. Although the Women's Health Initiative is investigating dietary and hormonal factors in relation to bone density, it is not investigating the effects of exercise on r...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age 40-65 years.
• • Post-menopause (3-10.9 years) due to hysterectomy or natural menopause.
• • Post-menopausal females, 3-10 years past menopause (natural or surgical menopause); if subjects are currently taking hormone replacement therapy (HRT), they must be taking HRT for at least 1 year but no more than 6 years. The subjects must be relatively sedentary, not currently engaged in strength-training exercises.
• • Nonsmoker.
• • Cancer free for the last 5 years (treatment free for last 5 years) excluding skin cancers.
• • Resident of Tucson (48 out of 52 weeks of year).
• Exclusion Criteria:
• • History of bone fractures or currently have osteoporosis.
• • Currently taking medications that control cholesterol or alter bone mineral density.
• • Currently taking beta-blockers or steroids in large quantities/frequencies.
• • Currently participating in any other research study.
• • Amount of physical activity exceeds 120 minutes of moderate exercise per week. Moderate exercise examples: brisk walking, golfing, gardening, housework, house painting. Potential subject cannot be weight lifting.