Search / Trial NCT00000399

Bone Estrogen Strength Training

Launched by UNIVERSITY OF ARIZONA · Nov 3, 1999

Trial Information

Current as of December 26, 2024

Completed

Keywords

Estrogen Hormone Therapy Strength Training Exercise Postmenopause Disorder Prevention Osteoporosis Bone Mineral Density Bone Mass Cholesterol Body Composition

ClinConnect Summary

Osteoporotic fractures associated with low bone mineral density (BMD) are a significant public health problem for women, resulting in over 1 million fractures per year. The increasing incidence of fractures will make an already major health problem an even greater one in the future. Estimates of medical costs for the treatment of osteoporotic fractures are expected to increase from $14.8 billion in 1995 to $60 billion by 2020. Although the Women's Health Initiative is investigating dietary and hormonal factors in relation to bone density, it is not investigating the effects of exercise on r...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Age 40-65 years.
  • Post-menopause (3-10.9 years) due to hysterectomy or natural menopause.
  • Post-menopausal females, 3-10 years past menopause (natural or surgical menopause); if subjects are currently taking hormone replacement therapy (HRT), they must be taking HRT for at least 1 year but no more than 6 years. The subjects must be relatively sedentary, not currently engaged in strength-training exercises.
  • Nonsmoker.
  • Cancer free for the last 5 years (treatment free for last 5 years) excluding skin cancers.
  • Resident of Tucson (48 out of 52 weeks of year).
  • Exclusion Criteria:
  • History of bone fractures or currently have osteoporosis.
  • Currently taking medications that control cholesterol or alter bone mineral density.
  • Currently taking beta-blockers or steroids in large quantities/frequencies.
  • Currently participating in any other research study.
  • Amount of physical activity exceeds 120 minutes of moderate exercise per week. Moderate exercise examples: brisk walking, golfing, gardening, housework, house painting. Potential subject cannot be weight lifting.

Trial Officials

Timothy G. Lohman, PhD

Principal Investigator

University of Arizona College of Medicine

About University Of Arizona

The University of Arizona is a leading research institution dedicated to advancing healthcare through innovative clinical trials and studies. With a strong emphasis on interdisciplinary collaboration, the university leverages its extensive resources and expertise to explore new therapeutic approaches and enhance patient outcomes. Committed to ethical research practices and community engagement, the University of Arizona fosters an environment that promotes scientific discovery and the translation of research findings into clinical applications. Its clinical trial initiatives encompass a wide range of medical disciplines, reflecting the institution's mission to improve health and well-being locally and globally.

Locations

Tucson, Arizona, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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