Search / Trial NCT00000438

Naltrexone Treatment for Alcoholism

Launched by JOHNS HOPKINS UNIVERSITY · Nov 2, 1999

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Trial Information

Current as of September 08, 2024

Completed

Keywords

Description

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • * Meets criteria for alcohol dependence.
  • * Committed to alcohol abstinence as a treatment goal.
  • * Individuals will be required to identify two family members or close friends who are knowledgeable about their location, drinking behavior, and psychosocial status.
  • Exclusion Criteria:
  • * Meets criteria for any other psychoactive substance use disorder (excluding nicotine and caffeine).
  • * Meets criteria for a major psychiatric disorder and are in need of or currently undergoing pharmacotherapy.
  • * Females who are pregnant, lactating, or not using a reliable method of contraception.
  • * Currently experiencing a serious medical condition that would place them at risk or interfere with study participation.
  • * Experiencing acute hepatitis or liver failure or whose liver function test is more than 3 times normal.
  • * Have a history of severe allergies, multiple adverse drug reactions or known allergy to naltrexone.
  • * Vocabulary below the 5th grade reading level.
  • * Abnormal MRI scan.
  • * HIV infection due to the neurological sequelae.
  • * Significant central nervous system diseases.
  • * Seizure disorder or history of closed head trauma.
  • * Neuroendocrine disorders.
  • * Treatment with opiates within the last six months.

About Sponsor

The National Institute of Allergy and Infectious Diseases (NIAID, /ˈnaɪ.æd/) is one of the 27 institutes and centers that make up the National Institutes of Health (NIH), an agency of the United States Department of Health and Human Services (HHS). NIAID's mission is to conduct basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases.

Contacts

JC

Jennifer Cobb

Immunology at National Institute of Allergy and Infectious Diseases (NIAID)

Locations

Baltimore, Maryland, United States

People applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0