Cholesterol Reduction in Seniors Program (CRISP)
Launched by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (NHLBI) · Oct 27, 1999
Trial Information
Current as of May 10, 2025
Completed
Keywords
ClinConnect Summary
BACKGROUND:
Circulating levels of cholesterol, specifically cholesterol associated with the low-density lipoprotein (LDL) fraction, have been established by observational epidemiologic studies and by metabolic, pathologic, genetic studies in humans and selected animal models, and by randomized clinical trials as a major etiologic factor in coronary heart disease. The ratio between the percent reduction in coronary heart disease incidence and the percent reduction in cholesterol levels associated with treatment in randomized trials, approximately 2:1, is almost exactly that predicted by num...
Gender
ALL
Eligibility criteria
- • Men and women, ages 65 and older, with elevated low-density lipoprotein cholesterol levels between 159 and 221 mg/dl at entry.
About National Heart, Lung, And Blood Institute (Nhlbi)
The National Heart, Lung, and Blood Institute (NHLBI) is a leading component of the National Institutes of Health (NIH), dedicated to advancing research and clinical trials focused on cardiovascular, pulmonary, and hematologic diseases. With a mission to improve public health through innovative research, the NHLBI supports a wide range of studies aimed at understanding, preventing, and treating heart and lung conditions. By collaborating with academic institutions, healthcare providers, and patient communities, the NHLBI strives to translate scientific discoveries into effective clinical practices, ultimately enhancing the quality of life for individuals affected by these critical health issues.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
William Applegate
University of Tennessee
John Crouse
Bowman Gray School of Medicine
Donald Hunninghake
University of Minnesota
Robert Knopp
University of Washington
John LaRosa
George Washington University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials