A Study to Evaluate the Long-Term Effectiveness of Three Anti-HIV Drug Regimens in HIV Infected Patients Who Have Never Been Exposed to Highly Active Antiretroviral Therapy (HAART)

Launched by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIAID) · Aug 30, 2001

Keywords

ClinConnect Summary

Highly active antiretroviral therapy (HAART) regimens containing PIs, NNRTIs, or nucleoside reverse transcriptase inhibitors (NRTIs) have been shown to slow disease progression. However, the long-term consequences of initial therapy with a PI, an NNRTI, or both a PI and an NNRTI are not yet known, nor is the impact on future anti-HIV treatment regimens. Patients who experience virologic failure on a particular HAART regimen typically have not been studied for subsequent response to other HAART regimens. It is possible that a regimen which is initially the most potent may not be optimal if i...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • HIV infected
• • Agree to practice abstinence or to use barrier methods of birth control during the study
• • Are at least 13 years old or have signed informed consent from legal guardian for patients between the ages of 13 and 18
• Exclusion Criteria:
• • Have ever taken any anti-HIV drugs
• • Are unable to complete the study for any reason
• • Pregnancy
• • Breastfeeding
• • Any condition that, in the investigator's opinion, may interfere with the study

Trial Officials