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Search / Trial NCT00001174

Evaluation of the Genetics of Bipolar Disorder

Launched by NATIONAL INSTITUTE OF MENTAL HEALTH (NIMH) · Nov 3, 1999

Trial Information

Current as of March 19, 2025

Recruiting

Keywords

Affective Disorder Depression Genetic Polymorphisms Major Depression Genome Wide Scan Natural History Panic Disorder Bipolar Disorder

ClinConnect Summary

This clinical trial, called the "Evaluation of the Genetics of Bipolar Disorder," aims to find out which genes might influence a person's risk of developing bipolar disorder and related conditions. Researchers are particularly interested in understanding the genetic links to this mental health issue, which can affect mood and behavior.

If you are 18 years or older and have bipolar disorder, or if you are a close relative of someone who does, you may be eligible to participate. It's important that you can provide a blood or saliva sample safely and that you do not have active substance abuse issues. Participants will undergo a simple procedure to provide these samples, and in return, they will help researchers uncover important genetic information that could improve understanding and treatment of bipolar disorder. This study is currently looking for volunteers from all genders, and it’s a great opportunity to contribute to mental health research!

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • Age \> 18 yr
  • Able to provide informed consent
  • Bipolar disorder or related conditions not attributable to substance abuse, neurological disease; or a 1st or 2nd degree relative of an enrolled participant. Related conditions are defined as those found more often among relatives of people with bipolar disorder or which have been shown to be genetically correlated with bipolar disorder through molecular genetic studies. These include major depression, schizophrenia, panic disorder, and attention deficit hyperactivity disorder.
  • Able to safely provide a blood or saliva sample
  • EXCLUSION CRITERIA:
  • Active alcohol or substance abuse.
  • NIMH employees/staff and their immediate family members will be excluded from the study per NIMH policy.

Trial Officials

Francis J McMahon, M.D.

Principal Investigator

National Institute of Mental Health (NIMH)

About National Institute Of Mental Health (Nimh)

The National Institute of Mental Health (NIMH) is a leading federal agency dedicated to advancing the understanding and treatment of mental health disorders through innovative research and clinical trials. As part of the National Institutes of Health (NIH), NIMH focuses on a broad spectrum of mental health issues, including mood disorders, anxiety disorders, schizophrenia, and developmental disorders. By fostering collaboration among researchers, clinicians, and the community, NIMH aims to translate scientific discoveries into effective interventions and improve mental health outcomes for individuals across the lifespan. Through its commitment to rigorous research methodologies and ethical standards, NIMH plays a pivotal role in shaping the future of mental health care and policy.

Locations

Bethesda, Maryland, United States

People applied

SH

TH

2 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Discussion 0

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