Nctid:
NCT00001240
Payload:
{"hasResults"=>false, "derivedSection"=>{"miscInfoModule"=>{"versionHolder"=>"2024-12-20"}, "conditionBrowseModule"=>{"meshes"=>[{"id"=>"D015408", "term"=>"Gastrinoma"}, {"id"=>"D015043", "term"=>"Zollinger-Ellison Syndrome"}, {"id"=>"D000126", "term"=>"Achlorhydria"}], "ancestors"=>[{"id"=>"D018273", "term"=>"Carcinoma, Islet Cell"}, {"id"=>"D000230", "term"=>"Adenocarcinoma"}, {"id"=>"D002277", "term"=>"Carcinoma"}, {"id"=>"D009375", "term"=>"Neoplasms, Glandular and Epithelial"}, {"id"=>"D009370", "term"=>"Neoplasms by Histologic Type"}, {"id"=>"D009369", "term"=>"Neoplasms"}, {"id"=>"D010190", "term"=>"Pancreatic Neoplasms"}, {"id"=>"D004067", "term"=>"Digestive System Neoplasms"}, {"id"=>"D009371", "term"=>"Neoplasms by Site"}, {"id"=>"D004701", "term"=>"Endocrine Gland Neoplasms"}, {"id"=>"D004066", "term"=>"Digestive System Diseases"}, {"id"=>"D010182", "term"=>"Pancreatic Diseases"}, {"id"=>"D004700", "term"=>"Endocrine System Diseases"}, {"id"=>"D009384", "term"=>"Paraneoplastic Endocrine Syndromes"}, {"id"=>"D010257", "term"=>"Paraneoplastic Syndromes"}, {"id"=>"D005770", "term"=>"Gastrointestinal Neoplasms"}, {"id"=>"D005767", "term"=>"Gastrointestinal Diseases"}, {"id"=>"D010437", "term"=>"Peptic Ulcer"}, {"id"=>"D004378", "term"=>"Duodenal Diseases"}, {"id"=>"D007410", "term"=>"Intestinal Diseases"}, {"id"=>"D013272", "term"=>"Stomach Diseases"}, {"id"=>"D000137", "term"=>"Acid-Base Imbalance"}, {"id"=>"D008659", "term"=>"Metabolic Diseases"}], "browseLeaves"=>[{"id"=>"M16355", "name"=>"Syndrome", "relevance"=>"LOW"}, {"id"=>"M12", "name"=>"Congenital Abnormalities", "relevance"=>"LOW"}, {"id"=>"M3490", "name"=>"Achlorhydria", "asFound"=>"Achlorhydria", "relevance"=>"HIGH"}, {"id"=>"M18083", "name"=>"Gastrinoma", "asFound"=>"Gastrinoma", "relevance"=>"HIGH"}, {"id"=>"M17778", "name"=>"Zollinger-Ellison Syndrome", "asFound"=>"Zollinger-Ellison Syndrome", "relevance"=>"HIGH"}, {"id"=>"M5534", "name"=>"Carcinoma", "relevance"=>"LOW"}, {"id"=>"M20418", "name"=>"Carcinoma, Islet Cell", "relevance"=>"LOW"}, {"id"=>"M3585", "name"=>"Adenocarcinoma", "relevance"=>"LOW"}, {"id"=>"M12320", "name"=>"Neoplasms, Glandular and Epithelial", "relevance"=>"LOW"}, {"id"=>"M12315", "name"=>"Neoplasms by Histologic Type", "relevance"=>"LOW"}, {"id"=>"M13110", "name"=>"Pancreatic Neoplasms", "relevance"=>"LOW"}, {"id"=>"M8886", "name"=>"Gastrointestinal Neoplasms", "relevance"=>"LOW"}, {"id"=>"M7256", "name"=>"Digestive System Neoplasms", "relevance"=>"LOW"}, {"id"=>"M7863", "name"=>"Endocrine Gland Neoplasms", "relevance"=>"LOW"}, {"id"=>"M8883", "name"=>"Gastrointestinal Diseases", "relevance"=>"LOW"}, {"id"=>"M7255", "name"=>"Digestive System Diseases", "relevance"=>"LOW"}, {"id"=>"M13102", "name"=>"Pancreatic Diseases", "relevance"=>"LOW"}, {"id"=>"M7862", "name"=>"Endocrine System Diseases", "relevance"=>"LOW"}, {"id"=>"M13170", "name"=>"Paraneoplastic Syndromes", "relevance"=>"LOW"}, {"id"=>"M17206", "name"=>"Ulcer", "relevance"=>"LOW"}, {"id"=>"M13348", "name"=>"Peptic Ulcer", "relevance"=>"LOW"}, {"id"=>"M7552", "name"=>"Duodenal Diseases", "relevance"=>"LOW"}, {"id"=>"M10444", "name"=>"Intestinal Diseases", "relevance"=>"LOW"}, {"id"=>"M16062", "name"=>"Stomach Diseases", "relevance"=>"LOW"}, {"id"=>"M3498", "name"=>"Acid-Base Imbalance", "relevance"=>"LOW"}, {"id"=>"M11639", "name"=>"Metabolic Diseases", "relevance"=>"LOW"}, {"id"=>"T6029", "name"=>"Zollinger-Ellison Syndrome", "asFound"=>"Zollinger-Ellison Syndrome", "relevance"=>"HIGH"}, {"id"=>"T4387", "name"=>"Pancreatic Cancer", "relevance"=>"LOW"}], "browseBranches"=>[{"name"=>"Symptoms and General Pathology", "abbrev"=>"BC23"}, {"name"=>"All Conditions", "abbrev"=>"All"}, {"name"=>"Diseases and Abnormalities at or Before Birth", "abbrev"=>"BC16"}, {"name"=>"Digestive System Diseases", "abbrev"=>"BC06"}, {"name"=>"Nutritional and Metabolic Diseases", "abbrev"=>"BC18"}, {"name"=>"Neoplasms", "abbrev"=>"BC04"}, {"name"=>"Gland and Hormone Related Diseases", "abbrev"=>"BC19"}, {"name"=>"Rare Diseases", "abbrev"=>"Rare"}]}}, "protocolSection"=>{"designModule"=>{"studyType"=>"OBSERVATIONAL"}, "statusModule"=>{"overallStatus"=>"COMPLETED", "startDateStruct"=>{"date"=>"1989-01"}, "expandedAccessInfo"=>{"hasExpandedAccess"=>false}, "statusVerifiedDate"=>"2004-01", "completionDateStruct"=>{"date"=>"2004-01"}, "lastUpdateSubmitDate"=>"2008-03-04", "studyFirstSubmitDate"=>"1999-11-03", "studyFirstSubmitQcDate"=>"1999-11-03", "lastUpdatePostDateStruct"=>{"date"=>"2008-03-05", "type"=>"ESTIMATED"}, "studyFirstPostDateStruct"=>{"date"=>"1999-11-04", "type"=>"ESTIMATED"}}, "conditionsModule"=>{"keywords"=>["Stomach", "Hypersecretion", "Hyposecretion", "Gastrinoma", "Zollinger-Ellison Syndrome"], "conditions"=>["Achlorhydria", "Gastrinoma", "Zollinger Ellison Syndrome"]}, "referencesModule"=>{"references"=>[{"pmid"=>"3972233", "type"=>"BACKGROUND", "citation"=>"McArthur KE, Collen MJ, Maton PN, Cherner JA, Howard JM, Ciarleglio CA, Cornelius MJ, Jensen RT, Gardner JD. Omeprazole: effective, convenient therapy for Zollinger-Ellison syndrome. Gastroenterology. 1985 Apr;88(4):939-44. doi: 10.1016/s0016-5085(85)80011-1."}, {"pmid"=>"2857672", "type"=>"BACKGROUND", "citation"=>"Howard JM, Chremos AN, Collen MJ, McArthur KE, Cherner JA, Maton PN, Ciarleglio CA, Cornelius MJ, Gardner JD, Jensen RT. Famotidine, a new, potent, long-acting histamine H2-receptor antagonist: comparison with cimetidine and ranitidine in the treatment of Zollinger-Ellison syndrome. Gastroenterology. 1985 Apr;88(4):1026-33. doi: 10.1016/s0016-5085(85)80024-x."}, {"pmid"=>"2877575", "type"=>"BACKGROUND", "citation"=>"Vinayek R, Howard JM, Maton PN, Wank SA, Slaff JI, Gardner JD, Jensen RT. Famotidine in the therapy of gastric hypersecretory states. Am J Med. 1986 Oct 24;81(4B):49-59. doi: 10.1016/0002-9343(86)90600-5."}]}, "descriptionModule"=>{"briefSummary"=>"This study is used by the Digestive Diseases Branch to evaluate patients with suspected abnormalities in the secretion of gastric acid. The level of gastric acid is measured by analyzing the gastric juices of each individual patient. The gastric acid sample is obtained by a procedure known as nasogastric suctioning, where a thin plastic tube is passed from the nose to the stomach.\n\nDepending on the patient's present condition further diagnostic testing may be required to achieve a diagnosis.", "detailedDescription"=>"This study is an omnibus protocol used by the Digestive Diseases Branch to evaluate patients with suspected abnormalities of gastric acid secretion. Gastric acid secretion is measured by means of analysis of gastric juices obtained by nasogastric suction. Other clinically indicated diagnostic procedures are performed depending on the patient's clinical state in order to reach a diagnosis."}, "eligibilityModule"=>{"sex"=>"ALL", "stdAges"=>["CHILD", "ADULT", "OLDER_ADULT"], "healthyVolunteers"=>false, "eligibilityCriteria"=>"Eligibility criteria not identified in the protocol."}, "identificationModule"=>{"nctId"=>"NCT00001240", "briefTitle"=>"Evaluating Patients With Abnormal Levels of Gastric Acid", "organization"=>{"class"=>"NIH", "fullName"=>"National Institutes of Health Clinical Center (CC)"}, "officialTitle"=>"Diagnostic Evaluation of Patients With Suspected Abnormalities of Gastric Secretion", "orgStudyIdInfo"=>{"id"=>"890005"}, "secondaryIdInfos"=>[{"id"=>"89-DK-0005"}]}, "contactsLocationsModule"=>{"locations"=>[{"zip"=>"20892", "city"=>"Bethesda", "state"=>"Maryland", "country"=>"United States", "facility"=>"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "geoPoint"=>{"lat"=>38.98067, "lon"=>-77.10026}}]}, "sponsorCollaboratorsModule"=>{"leadSponsor"=>{"name"=>"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "class"=>"NIH"}}}}
