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Search / Trial NCT00001276

Diagnosing and Treating Low Blood Sugar Levels

Launched by NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK) · Nov 3, 1999

Trial Information

Current as of May 10, 2025

Recruiting

Keywords

Hypoglycemia Insulinoma Natural History

ClinConnect Summary

This clinical trial is studying low blood sugar levels, also known as hypoglycemia, and a specific condition called insulinoma, which is a type of tumor in the pancreas that can cause these low levels. The researchers want to understand the causes of hypoglycemia better and how to diagnose and treat it. Patients who join the study will spend time at the Clinical Center of the National Institutes of Health, where they will have to fast (not eat) for a certain period. During this time, they will undergo blood tests to check their blood sugar and insulin levels, and they will be monitored closely by medical staff to ensure their safety.

To be eligible for this study, participants need to be at least 18 years old and have experienced low blood sugar levels (below 55 mg/dl) along with signs of insulinoma or other related tumors. However, individuals with serious heart conditions, pregnant women, or those who are not medically stable cannot participate. This trial aims to provide valuable information that could help improve the diagnosis and treatment of low blood sugar conditions in the future.

Gender

ALL

Eligibility criteria

  • * INCLUSION CRITERIA:
  • In order to be eligible to participate in this study, an individual must meet all of the following criteria:
  • 1. Male, females ages \>= 18.
  • 2. Patients with documented fasting blood glucose below 55 mg/dl.
  • 4. Patients with biochemical evidence for insulinoma or other pancreatic neuroendocrine tumors.
  • EXCLUSION CRITERIA:
  • An individual who meets any of the following criteria will be excluded from participation in this study:
  • 1. Patients with significant cardiac disease will be excluded.
  • 2. Subjects who are pregnant per self-report.
  • 3. Medically unstable per the assessment of the PI.

About National Institute Of Diabetes And Digestive And Kidney Diseases (Niddk)

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is a prominent research institution within the National Institutes of Health (NIH) dedicated to advancing scientific knowledge and promoting health in the areas of diabetes, endocrine and metabolic disorders, obesity, digestive diseases, and kidney diseases. Through rigorous clinical trials and innovative research initiatives, NIDDK aims to improve prevention, diagnosis, and treatment strategies, ultimately enhancing patient outcomes and quality of life. The institute fosters collaboration among researchers, healthcare professionals, and community stakeholders to drive impactful discoveries and translate findings into effective healthcare solutions.

Locations

Bethesda, Maryland, United States

Bethesda, Maryland, United States

Patients applied

0 patients applied

Trial Officials

Ranganath Muniyappa, M.D.

Principal Investigator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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